NCT00259181

Brief Summary

Chlorhexidine gluconate (CHX), as an anti plaque agent, is commonly used with a variety of products. In this study we, the investigators at Hadassah Medical Organization, intend to examine the efficacy of a single dip in CHX of provisional restoration prior to oral cementation. If the protocol is effective, we intend to calibrate it and recommend clinical use of the protocol. The examination of biofilm formation will be both with electron microscope and confocal scanning laser microscope.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

November 24, 2005

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 29, 2005

Completed
Last Updated

January 6, 2010

Status Verified

December 1, 2007

First QC Date

November 24, 2005

Last Update Submit

January 5, 2010

Conditions

Dental Plaque

Keywords

chlorhexidine gluconatepolymethylmethacrylateAnti-Bacterial Agents

Outcome Measures

Primary Outcomes (1)

  • calibration of a preventative protocol for biofilm formation measured by confocal scanning laser microscope and scanning electron microscope

Interventions

saturation of polymethylmethacrylate with chlorhexidine gluconate to reduce in vivo plaque formationPROCEDURE

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Any volunteer without systemic condition

You may not qualify if:

  • Intake of antibiotic drug three months prior to experiment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah Medical Organization

Jerusalem, 91120, Israel

Location

Related Links

MeSH Terms

Conditions

Dental Plaque

Condition Hierarchy (Ancestors)

Dental DepositsTooth DiseasesStomatognathic Diseases

Study Officials

  • Michael M Perez Davidi, DMD

    Hadassah Medical Organization

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NON RANDOMIZED
Masking
SINGLE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 24, 2005

First Posted

November 29, 2005

Study Start

January 1, 2005

Last Updated

January 6, 2010

Record last verified: 2007-12

Locations

IL(1)