Effect of Provisional-Crown Surface Coating on Biofilm Formation

NCT00254345 | Completed Phase 1

• 1 other identifier: 191056HMO-CTIL
• Study Type: interventional
• Target: 1
• Locations: 1 country
• Sites: 1

Brief Summary

Auto polymerizing poly methyl methacrylate (PMMA), and light initiated resin modified PMMAs, are commonly used for fabricating provisional restorations (PRs) during prosthetic treatment 1. Biofilm accumulated on these PRs may cause caries and inflammation of the surrounding tissue, tempering the outcome of the final restoration 2. Plaque adherence to temporary restorations was significantly increased compared with the untreated reference teeth 3. Biologic and physical properties of the various materials used as PRs were studied extensively 4-8 whereas their interaction with bacterial biofilm in vivo and ex vivo is less characterized. One improvement in provisional restorative materials is the use of liquid polish. It is claimed that these materials gives a high luster finish to provisional bis-acryl restorations and processed acrylic appliances, reduces or eliminates costly and time consuming polishing steps and can be used on all types of direct and indirect restorations and appliances.The effect of liquid polish coating or resin bonding coating on biofilm formation on PRs was not reported.

Conditions

Dental Plaque

Keywords

biofilm; adhesion; liquid polish; bonding resin; PMMA Polymethylmetacrylate; provisional crown; no antibiotics treatment three months prior to experiment; no mouth rinse with oral solutions one month prior to experiment

Outcome Measures

Primary Outcomes (1)

• surface coating with reduced biofilm formation demonstrated by confocal scanning laser microscope and scanning electron microscope

Interventions

coating a dental restoration material ,polymethylmethacrylate, with liquid polish resin PROCEDURE

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient in need for PMAA provisional crowns

You may not qualify if:

• Patient took antibiotics three months prior to experiment

Sponsors & Collaborators

• Hadassah Medical Organization: lead

Study Sites (1)

Hadassah Medical Organization,

Jerusalem, 91120, Israel

Location

Related Publications (1)

• Perez Davidi M, Beyth N, Sterer N, Feuerstein O, Weiss EI. Effect of liquid-polish coating on in vivo biofilm accumulation on provisional restorations: part 1. Quintessence Int. 2007 Jul-Aug;38(7):591-6.

  PMID: 17694216 RESULT

Related Links

• Michael Perez Davidi

MeSH Terms

Conditions

Dental Plaque; Tissue Adhesions

Condition Hierarchy (Ancestors)

Dental Deposits; Tooth Diseases; Stomatognathic Diseases; Cicatrix; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Michael M Perez Davidi, DMD

  Hadassah Medical Organization

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: November 15, 2005
• First Posted: November 16, 2005
• Study Start: September 1, 2006
• Study Completion: April 1, 2007
• Last Updated: December 11, 2007

Record last verified: 2007-12

Locations

IL (1)