NCT00255554

Brief Summary

Subjects will receive six months of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist. Half the subjects will concurrently receive escitalopram while half will receive placebo, in a randomized double-blind design.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 17, 2005

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 21, 2005

Completed
Last Updated

November 21, 2005

Status Verified

November 1, 2005

First QC Date

November 17, 2005

Last Update Submit

November 17, 2005

Conditions

Borderline Personality Disorder

Keywords

Borderline Personality DisorderBPDDialectical Behavior TherapyDBTEscitalopramLexapro

Outcome Measures

Primary Outcomes (1)

  • Measures of impulsivity, aggression, affective impulsivity, immediate and delayed memory, and cognitive processing at baseline, 6 months and 9 months

Interventions

Dialectical Behavioral TherapyBEHAVIORAL
EscitalopramDRUG

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bronx VA Medical Center

The Bronx, New York, 10029, United States

RECRUITING

Related Publications (1)

  • Stoffers-Winterling JM, Storebo OJ, Pereira Ribeiro J, Kongerslev MT, Vollm BA, Mattivi JT, Faltinsen E, Todorovac A, Jorgensen MS, Callesen HE, Sales CP, Schaug JP, Simonsen E, Lieb K. Pharmacological interventions for people with borderline personality disorder. Cochrane Database Syst Rev. 2022 Nov 14;11(11):CD012956. doi: 10.1002/14651858.CD012956.pub2.

    PMID: 36375174DERIVED

MeSH Terms

Conditions

Borderline Personality Disorder

Interventions

Escitalopram

Condition Hierarchy (Ancestors)

Personality DisordersMental Disorders

Intervention Hierarchy (Ancestors)

PropylaminesAminesOrganic ChemicalsNitrilesBenzofuransHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-RingHeterocyclic Compounds

Study Officials

  • Marianne Goodman, MD

    Bronx VA Medical Center/Mount Sinai School of Medicine

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Emily Hart

CONTACT

212-241-0441mpgroup@mssm.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED

Study Record Dates

First Submitted

November 17, 2005

First Posted

November 21, 2005

Last Updated

November 21, 2005

Record last verified: 2005-11

Locations

US(1)