CANDIS - Targeted Treatment for Cannabis Disorders
CANDIS -Targeted Treatment for Cannabis Disorders
1 other identifier
interventional
210
1 country
1
Brief Summary
The purpose of this study is to develop a modular treatment program for cannabis use disorders and the evaluation of the effectiveness in a controlled clinical study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_2
Started Jan 2006
Shorter than P25 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 14, 2005
CompletedFirst Posted
Study publicly available on registry
November 15, 2005
CompletedStudy Start
First participant enrolled
January 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2007
CompletedJanuary 17, 2007
January 1, 2007
November 14, 2005
January 15, 2007
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
- total quit rates, defined as no evidence of cannabis use during the past 4 weeks as evidenced by self report and a negative urine screen; number of times a cannabis product was used in the past 4 weeks
; decrease in ASI total score; retention rate
Secondary Outcomes (1)
- number of slips; relapse; abstinence from all legal drugs; number of times of drug use other than cannabis
Interventions
Eligibility Criteria
You may qualify if:
- age 16 or older
- lifetime diagnosis of cannabis abuse or cannabis dependence (according to the DSM-IV criteria
- current (4 wks) regular cannabis use (at least 2 days a week)
- persistent history of regular cannabis use of at least 3 years
- informed consent to the study procedures and assessments
You may not qualify if:
- current alcohol or any illicit drug dependence syndrome according to DSM-IV other than due to cannabis
- lifetime history of any psychotic disorder
- current severe episode of Major depression
- current panic-agoraphobic disorder (severe)
- severe learning disability, brain damage or pervasive developmental disorder
- currently acute suicidality
- not fluent in german language
- acute signs of intoxication at screening or baseline assessment due to opiates or any type of stimulants, causing cognitive impairments
- currently in treatment for cannabis-related disorders in other services
- current psychotropic medications with sedatives and antipsychotics
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department for Clinical Psychology and Psychotherapy; Technical University of Dresden
Dresden, Germany
Related Publications (1)
Hoch E, Noack R, Henker J, Pixa A, Hofler M, Behrendt S, Buhringer G, Wittchen HU. Efficacy of a targeted cognitive-behavioral treatment program for cannabis use disorders (CANDIS). Eur Neuropsychopharmacol. 2012 Apr;22(4):267-80. doi: 10.1016/j.euroneuro.2011.07.014. Epub 2011 Aug 24.
PMID: 21865014DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Eva Hoch, PhD
Departement of Clinical Psychology and Psychotherapy, Dresden University of Technology
- STUDY DIRECTOR
Hans-Ulrich Wittchen, PhD
Departement of Clinical Psychology and Psychotherapy, Dresden University of Technology
- STUDY DIRECTOR
Gerhard Bühringer, PhD
Departement of Clinical Psychology and Psychotherapy, Dresden University of Technology
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
November 14, 2005
First Posted
November 15, 2005
Study Start
January 1, 2006
Study Completion
March 1, 2007
Last Updated
January 17, 2007
Record last verified: 2007-01