Cannabis Use Disorder
103
31
35
42
Key Insights
Highlights
Success Rate
89% trial completion (above average)
Treatment Research
20 treatments under study, led by Dronabinol
Published Results
22 trials with published results (21%)
Research Leaders
20 sponsors active, led by National Institute on Drug Abuse (NIDA)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 37/100
4.9%
5 terminated out of 103 trials
89.4%
+2.8% vs benchmark
8%
8 trials in Phase 3/4
52%
22 of 42 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 42 completed trials
Clinical Trials (103)
Cannabinoids and Biological Reactivity to Stress
Study of an Oral Fluid Testing Approach
Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
Semaglutide for the Treatment of Cannabis Use Disorder
SV2 PET Imaging With [11C]APP311
Tirzepatide for the Treatment of Cannabis Use Disorder
Sex Differences in Neurobehavioral Response to THC
Endocannabinoids in Reward
Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder and Cannabis Use Disorder
Lemborexant for Cannabis Use Disorder
Trial of Tirzepatide for the Treatment of Cannabis Use Disorder
Comparing the Spanish Version of CANreduce With or Without Psychological Support and Treatment as Usual, Reducing Cannabis Use.
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Regulated Cannabis Access in Basel
Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans
Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing
Developing a Telehealth + mHealth Cannabis Use Intervention for Young Adults
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Pregnenolone for Cannabis Use Disorder and Depression
Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)
Research Network
Common Treatments
- Dronabinol6
- Contingency Management4
- Repetitive Transcranial Magnetic Stimulation Rtms3
- Cannabidiol3
- Varenicline3
Active Sponsors
- National Institute on Drug Abuse (NIDA)49
- Medical University of South Carolina12
- Yale University7
- Centre for Addiction and Mental Health7
- Massachusetts General Hospital6
Top Investigators
University of Montreal, Institut universitaire en santé mentale de Montréal
Florida State University
Centre for Addiction and Mental Health
NYU Langone Health
Dept. of Emergency Medicine, Queen's University
Related Conditions
- Cannabis Dependence9
- Cannabis Use6
- Schizophrenia5
- Cannabis Abuse5
- Alcohol Use Disorder5