NCT00251108

Brief Summary

The aim of this project is to compare the efficacy of two different fitness exercise programmes on improving fitness and psychosocial functioning in a traumatic brain injured population. We hypothesize that a supervised fitness-centre based exercise programme, compared to an unsupervised home-based exercise programme will show significant improvements in cardiorespiratory fitness, depression and community integration.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2003

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2003

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

November 8, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 9, 2005

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2007

Completed
Last Updated

March 1, 2007

Status Verified

February 1, 2007

First QC Date

November 8, 2005

Last Update Submit

February 28, 2007

Conditions

Keywords

'traumatic brain injury''head injury''brain injuries''exercise therapy''physical fitness'

Outcome Measures

Primary Outcomes (1)

  • Measure of Cardiorespiratory fitness:Modified 20 metre Walk/Run Shuttle Test:

Secondary Outcomes (7)

  • Depression Anxiety Stress Scales (DASS)

  • Profile of Moods Scale (POMS)

  • BICRO-39

  • Sydney Psychosocial Reintegration Scale (SPRS)

  • Body Mass Index (BMI)

  • +2 more secondary outcomes

Interventions

Eligibility Criteria

Age15 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • have sustained a very severe or extremely severe traumatic brain injury
  • have had a hospital admission of \> 1 month
  • are able to walk independently at \> 1 m/s on discharge
  • are able to commit 3 hours per week to a fitness programme
  • live within the area serviced by the 3 units

You may not qualify if:

  • have a concurrent medical condition for which moderate to high intensity exercise is contraindicated
  • are still in Posttraumatic Amnesia (PTA)
  • have cognitive or language problems that affect their ability to understand verbal instructions
  • have behaviour problems not suitable for a fitness centre environment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Brain Injury Rehabilitation Unit, Royal Rehabilitation Centre Sydney

Sydney, New South Wales, 1680, Australia

Location

Brain Injury Rehabilitation Unit, Liverpool Health Service

Sydney, New South Wales, 2117, Australia

Location

Brain Injury Rehabilitation Unit, Westmead Hospital

Sydney, New South Wales, 2145, Australia

Location

MeSH Terms

Conditions

Craniocerebral TraumaBrain Injuries, TraumaticBrain Injuries

Condition Hierarchy (Ancestors)

Trauma, Nervous SystemNervous System DiseasesWounds and InjuriesBrain DiseasesCentral Nervous System Diseases

Study Officials

  • Leanne M Hassett, MHSc

    Brain Injury Rehabilitation Unit, Liverpool Health Service, SSWAHS

    PRINCIPAL INVESTIGATOR
  • Robyn Tate, PhD

    Rehabilitation Studies Unit, Royal Rehabilitation Centre Sydney

    PRINCIPAL INVESTIGATOR
  • Anne M Moseley, PhD

    University of Sydney

    PRINCIPAL INVESTIGATOR
  • Alison R Harmer, PhD

    University of Sydney

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

November 8, 2005

First Posted

November 9, 2005

Study Start

October 1, 2003

Study Completion

March 1, 2007

Last Updated

March 1, 2007

Record last verified: 2007-02

Locations