Coronary Heart Disease Incidence: Depression & Inflammation Risk
2 other identifiers
observational
3,227
1 country
1
Brief Summary
To examine the associations among depression, inflammation, and coronary heart disease using an existing data base and associated plasma samples.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2005
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2005
CompletedFirst Submitted
Initial submission to the registry
October 17, 2005
CompletedFirst Posted
Study publicly available on registry
October 19, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2010
CompletedFebruary 5, 2016
February 1, 2016
4.6 years
October 17, 2005
February 4, 2016
Conditions
Study Arms (1)
NSHS95 samples
In 1995, our study participants enrolled in the Nova Scotia Health Study (NSHS95). At the time of enrollment, epidemiologic data as well as blood samples were obtained. The participants have since been followed prospectively for a variety of health outcomes. We plan to assay stored blood samples collected in 1995 for markers of inflammation and link these results to existing epidemiologic and outcomes data, specifically the 7- year incidence of CAD events.
Eligibility Criteria
In 1995, our study participants enrolled in the Nova Scotia Health Study (NSHS95). At the time of enrollment, epidemiologic data as well as blood samples were obtained. The participants have since been followed prospectively for a variety of health outcomes. We plan to assay stored blood samples collected in 1995 for markers of inflammation and link these results to existing epidemiologic and outcomes data, specifically the 7-year incidence of CAD events.
You may qualify if:
- Age 18 and over
- Able to speak English
- Enrolled in the Nova Scotia Health Study (NSHS95)
You may not qualify if:
- Pregnant
- Active military personnel
- Lived in Nova Scotia province for less than 3 months
- Unable to provide informed consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Columbia University
New York, New York, 10032, United States
Related Links
Biospecimen
In 1995, our study participants enrolled in the Nova Scotia Health Study (NSHS95). At the time of enrollment, epidemiologic data as well as blood samples were obtained. The participants have since been followed prospectively for a variety of health outcomes. We plan to assay stored blood samples collected in 1995 for markers of inflammation and link these results to existing epidemiologic and outcomes data, specifically the 7-year incidence of CAD events. Buffy coats were also obtained from the blood samples of the SAME participants for future DNA analysis.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Karina Davidson, PhD
Columbia University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Behavioral Medicine
Study Record Dates
First Submitted
October 17, 2005
First Posted
October 19, 2005
Study Start
August 1, 2005
Primary Completion
March 1, 2010
Study Completion
May 1, 2010
Last Updated
February 5, 2016
Record last verified: 2016-02