NCT00236548

Brief Summary

The purpose of this study is to assess the usefulness of the Risperdal® Consta® Treatment Guidebook in helping the doctor switch the adult patient from taking risperidone tablets daily by mouth to taking long-acting risperidone by injection. The study will also evaluate the effectiveness and safety of long-acting risperidone and its effect on patient satisfaction.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for phase_3 schizophrenia

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Completion

Last participant's last visit for all outcomes

January 1, 2003

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

October 7, 2005

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 12, 2005

Completed
Last Updated

May 18, 2011

Status Verified

March 1, 2011

First QC Date

October 7, 2005

Last Update Submit

May 17, 2011

Conditions

Keywords

Schizophreniaschizoaffective disorderpatient compliancelong-acting risperidoneintramuscular injectionTreatment Guidebook

Outcome Measures

Primary Outcomes (1)

  • Usefulness of the Risperdal® Consta® Treatment Guidebook; patient and clinician adherence to guidelines

Secondary Outcomes (1)

  • Effectiveness of study drug measured by the Clinical Global Impression scale; safety by assessing treatment-emergent adverse events, vital signs, laboratory tests or electrocardiogram changes; quality of life by the Schizophrenia Quality of Life Scale

Interventions

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of schizophrenia or schizoaffective disorder
  • stable with respect to disease symptoms and other medical conditions
  • taking oral risperidone at doses of 2 to 6 milligrams per day for 4 weeks before start of study
  • if female, using birth control.

You may not qualify if:

  • Hospitalized within past 4 weeks to treat exacerbation of symptoms of schizophrenia
  • at risk for injury to self or others
  • had electroconvulsive therapy within past year
  • presence of liver or kidney impairment
  • use of oral antipsychotics (other than risperidone) within past 4 weeks, of injected antipsychotics within past 3 months, of clozapine within past 60 days, or of long-acting risperidone in an earlier study
  • pregnant or breast-feeding
  • not using birth control
  • abusing drugs or alcohol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

MeSH Terms

Conditions

SchizophreniaPsychotic DisordersPatient Compliance

Interventions

Risperidone

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic DisordersMental DisordersPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Intervention Hierarchy (Ancestors)

PyrimidinonesPyrimidinesHeterocyclic Compounds, 1-RingHeterocyclic Compounds

Study Officials

  • Johnson & Johnson Pharmaceutical Research & Development, L.L. C. Clinical Trial

    Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

October 7, 2005

First Posted

October 12, 2005

Study Completion

January 1, 2003

Last Updated

May 18, 2011

Record last verified: 2011-03