NCT00234689

Brief Summary

Assessing the efficacy of Naltrexone as augmentation to SSRI in patients with OCD

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jan 2002

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2002

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2004

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2004

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

October 6, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 7, 2005

Completed
Last Updated

January 30, 2008

Status Verified

January 1, 2008

Enrollment Period

2.9 years

First QC Date

October 6, 2005

Last Update Submit

January 28, 2008

Conditions

Obsessive Compulsive Disorder

Interventions

NaltrexoneDRUG

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of OCD
  • Treatment with SSRI for at least 10 weeks with no response

You may not qualify if:

  • Suffering from any medical condition
  • treatment with opiates
  • chronic use of drugs
  • Hepatitis or other liver related diseases
  • Incapability to sign an informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chaim Sheba Medical Center

Ramat Gan, 52621, Israel

Location

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Naltrexone

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Intervention Hierarchy (Ancestors)

NaloxoneMorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic Compounds

Study Officials

  • Joseph Zohar, MD

    Tel Aviv University

    PRINCIPAL INVESTIGATOR

  • Revital Amiaz, MD

    Tel Aviv University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Intervention Model
CROSSOVER
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

October 6, 2005

First Posted

October 7, 2005

Study Start

January 1, 2002

Primary Completion

December 1, 2004

Study Completion

December 1, 2004

Last Updated

January 30, 2008

Record last verified: 2008-01

Locations

IL(1)