The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Risk Behaviors (Drug and Alcohol Use, Sexual Risk Behavior, Poor Adherence to Medications) Among HIV+ Youth. - 1

NCT00227825 | Unknown Phase 2 DMC

• 2 other identifiers: NIDA-14710-1R21-14710-1
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to conduct a pilot study of Motivational Enhancement Therapy (MET), an empirically validated behavioral change strategy, with young adults who are HIV +. The aim is to determine if MET is effective in increasing general health promotion behaviors, adherence to HIV+ specific medical treatment over and above taking medication, and decreasing risky behaviors in young adults who are HIV positive. The longer-term objective is to identify and way to decrease HIV transmission rates, disease progression, illness episodes, and hospitalizations in this high-risk population. Hypotheses: 1)Youth receiving the motivational intervention plus referrals will report greater reductions in risky behaviors than youth in the control group receiving standard care plus referrals at 3-months post-baseline. This hypothesis will first be tested in the whole sample using an overall risk index. Then, the hypothesis will be tested with each behavior (reduced drug and alcohol use, condom use, taking medications,) within the subgroups reporting problem levels of that behavior; 2)Youth in the intervention group will demonstrate improved viral loads, will report greater improvement in perceived health status, depression, general psychological distress, disclosure to sexual partners, and will demonstrate greater attendance of medical and support service appointments than youth in the control group at 3 months post-baseline; 3)Youth in the intervention group will report greater reductions in temptation to engage in risky behaviors, increased self-efficacy, and improvements in readiness to change their behavior than youth in the control group at 3 months post-baseline; 4)The differences between the intervention and control group from pre- to post- intervention will be maintained at 6, 9, 12, and 15 months post-baseline (3, 6, 9, and 12 months after intervention completion).

Conditions

Adherence; HIV Risk Behaviors; Alcohol & Drug Use; Health Behaviors; Sexual Risk Behaviors

Keywords

Behavioral Intervention

Outcome Measures

Primary Outcomes (1)

• Reduction of Risk Behaviors (Sexual, Drug, & Health), Viral Burden & CD4+ T Cell Count

Secondary Outcomes (1)

• SES, health beliefs, physical and mental status, self-efficacy, stages of change, service utilization, HIV stigma

Interventions

Motivational interviewing BEHAVIORAL

Eligibility Criteria

• Age: 16 Years - 24 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• A sample of 60 HIV+youth, ages 16-24, will be recruited from the four health care sites in the Michigan Title IV Project.

Sponsors & Collaborators

• National Institute on Drug Abuse (NIDA): lead
• Wayne State University: collaborator

Study Sites (1)

Detroit Medical Center-CHM and UHC

Detroit, Michigan, 48201, United States

Location

MeSH Terms

Conditions

Substance-Related Disorders; Health Behavior

Interventions

Motivational Interviewing

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders; Behavior

Intervention Hierarchy (Ancestors)

Directive Counseling; Counseling; Mental Health Services; Behavioral Disciplines and Activities; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Sylvie Naar-King, Ph.D.

  Wayne State University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Phebe K Lam, M.A.

CONTACT

(313)745-4213; plam@med.wayne.edu

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 27, 2005
• First Posted: September 28, 2005
• Study Start: January 1, 2002
• Study Completion: August 1, 2005
• Last Updated: January 11, 2017

Record last verified: 2005-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)