Task-Related Training of Arm Use After Stroke
1 other identifier
interventional
30
1 country
1
Brief Summary
Stroke is the leading cause of long-term physical disability in Australia. Currently around 25% of hemiplegic stroke patients discharged from rehabilitation have significantly impaired use of the affected hand with consequent dependence in dressing, grooming and feeding themselves. The poor outcome can be attributed in part to a lack of focus by therapists on the negative signs of stroke (weakness and lack of dexterity) as well as too little time (around 10 minutes per day) being devoted to retraining of the arm. Presently there is a very limited evidence base to guide the content of clinical practice. Results from both animal and human studies suggest that specific post-lesion training can result in substantial improvement in function. The hypothesis is that task-specific training of the affected upper limb to subjects in the early period following stroke will result in significantly better functional outcome than standard intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable stroke
Started Feb 2002
Typical duration for not_applicable stroke
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2002
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2004
CompletedFirst Submitted
Initial submission to the registry
September 13, 2005
CompletedFirst Posted
Study publicly available on registry
September 22, 2005
CompletedSeptember 22, 2005
December 1, 2001
September 13, 2005
September 13, 2005
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Arm and hand function measured using the Motor Assessment Scale and the Chedoke-McMaster Impairment Inventory.
Grip and pinch strength measured using dynamometers.
Secondary Outcomes (3)
Dexterity measured using the NK Dexterity Board
Quality of Life measured using the Stroke-adapted Sickness Impact Profile.
Sensation using a validated assessment of tactile spatial resolution.
Interventions
Eligibility Criteria
You may qualify if:
- within 6 weeks of first stroke
- unilateral stroke
- impaired arm function
- able to cope with intensive training program
- medically stable
- able to understand instructions
You may not qualify if:
- uncontrolled systemic disease
- significant musculotendinous or bony restrictions of the affected upper limb
- any serious chronic disease independently causing significant disability of the affected limb
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Austin Health
Melbourne, Victoria, 3084, Australia
Related Publications (1)
Miller K, Galea M, Kilbreath S, Phillips B (2002) Early intensive task-specific sensory and motor training of the upper limb following acute stroke: a pilot study. In Battistin L, Dam M, Tonin P(eds) Neurological Rehabilitation. Bologna:Mondizzi Editore.
RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mary P Galea, PhD
University of Melbourne
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 13, 2005
First Posted
September 22, 2005
Study Start
February 1, 2002
Study Completion
June 1, 2004
Last Updated
September 22, 2005
Record last verified: 2001-12