NCT00222066

Brief Summary

The purpose of this study is to determine whether prenatal ovarian cyst aspiration is effective and safe to prevent perinatal ovarian torsion.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
61

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2001

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2001

Completed
4.3 years until next milestone

First Submitted

Initial submission to the registry

September 19, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 22, 2005

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2007

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2007

Completed
Last Updated

February 3, 2010

Status Verified

September 1, 2006

Enrollment Period

5.6 years

First QC Date

September 19, 2005

Last Update Submit

February 2, 2010

Conditions

Keywords

AspirationFetal ovarian cystOvarian torsion

Outcome Measures

Primary Outcomes (1)

  • To avoid neonatal surgery

    3 months after birth

Secondary Outcomes (2)

  • Ultrasound pattern of neonatal ovarian cyst

    3 months after birth

  • Maternal and fetal/neonatal safety of prenatal ovarian cyst aspiration

    3 months after birth

Study Arms (2)

1

EXPERIMENTAL

Fetal ovarian cyst aspiration performed as soon as possible

Procedure: Fetal ovarian cyst aspiration

2

NO INTERVENTION

Expectative

Interventions

Fetal ovarian cyst aspiration performed under ultrasound guidance and maternal local anesthesia

1

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Pregnant women having an uneventful single pregnancy and a female fetus diagnosed with anechoic ovarian cyst (diameter at least 30mm)

You may not qualify if:

  • Multiple pregnancy
  • Complicated pregnancy (PE, diabetes, PROM, fetal malformation)
  • Echoic cyst (fluid debris level, septated, retracting clot, globally echoic)
  • Unability to give informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Olympe de Gouges Women Health Centre, Bretonneau University Hospital

Tours, Centre-Val de Loire, 37044, France

Location

CHU de Nantes

Nantes, Loire Atl, 44000, France

Location

CHU de Caen

Caen, France

Location

Related Publications (2)

  • Perrotin F, Potin J, Haddad G, Sembely-Taveau C, Lansac J, Body G. Fetal ovarian cysts: a report of three cases managed by intrauterine aspiration. Ultrasound Obstet Gynecol. 2000 Dec;16(7):655-9. doi: 10.1046/j.1469-0705.2000.00247.x.

    PMID: 11169374BACKGROUND
  • Perrotin F, Roy F, Potin J, Lardy H, Lansac J, Body G. [Ultrasonographic diagnosis and prenatal management of fetal ovarian cysts]. J Gynecol Obstet Biol Reprod (Paris). 2000 Apr;29(2):161-9. French.

    PMID: 10790628BACKGROUND

MeSH Terms

Conditions

Ovarian CystsNeonatal ovarian cystOvarian Torsion

Condition Hierarchy (Ancestors)

CystsNeoplasmsOvarian DiseasesAdnexal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital DiseasesGonadal DisordersEndocrine System DiseasesTorsion AbnormalityPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Officials

  • Franck Perrotin, MD--PhD

    Tours University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 19, 2005

First Posted

September 22, 2005

Study Start

June 1, 2001

Primary Completion

January 1, 2007

Study Completion

September 1, 2007

Last Updated

February 3, 2010

Record last verified: 2006-09

Locations