NCT00219687

Brief Summary

The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,494

participants targeted

Target at P75+ for phase_3

Timeline
Completed

Started Jun 2004

Longer than P75 for phase_3

Geographic Reach
2 countries

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2004

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

September 13, 2005

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 22, 2005

Completed
6.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2012

Completed
Last Updated

October 29, 2014

Status Verified

October 1, 2014

Enrollment Period

8.2 years

First QC Date

September 13, 2005

Last Update Submit

October 28, 2014

Conditions

Heart Arrest

Keywords

Heart arrestCardiopulmonary resuscitationDispatcher

Outcome Measures

Primary Outcomes (1)

  • Survival to hospital discharge

    assessed at hospital discharge

    varied

Secondary Outcomes (1)

  • Neurological status at hospital discharge

    varied

Study Arms (2)

1

ACTIVE COMPARATOR

When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions only

Other: dispatcher-assisted CPR instructions with compressions only

2

ACTIVE COMPARATOR

When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions and breaths

Other: dispatcher-assisted CPR with compressions & ventilations

Interventions

dispatcher-assisted CPR with compressions & ventilationsOTHER

Delivery of telephone CPR instructions to lay callers with chest compressions and ventilations when the patient is identified to be in cardiac arrest

2
dispatcher-assisted CPR instructions with compressions onlyOTHER

Delivery of telephone CPR instructions to lay callers with hands-only chest compressions when the patient is identified to be in cardiac arrest

1

Eligibility Criteria

Age9 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance

You may not qualify if:

  • Pregnancy
  • Prisoners
  • Cardiac arrest due to asphyxia, drowning, hanging, or electrocution

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Thurston County Dispatch

Olympia, Washington, United States

Location

Division of Emergency Medical Services, Public Health - Seattle and King County

Seattle, Washington, 98104, United States

Location

London Ambulance Service

London, England, United Kingdom

Location

Related Publications (1)

  • Rea TD, Fahrenbruch C, Culley L, Donohoe RT, Hambly C, Innes J, Bloomingdale M, Subido C, Romines S, Eisenberg MS. CPR with chest compression alone or with rescue breathing. N Engl J Med. 2010 Jul 29;363(5):423-33. doi: 10.1056/NEJMoa0908993.

    PMID: 20818863DERIVED

MeSH Terms

Conditions

Heart Arrest

Interventions

Ventilation

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Environment, ControlledEnvironmentEnvironment and Public Health

Study Officials

  • Thomas D Rea, MD, MPH

    Division of Emergency Medical Services, Public Health - Seattle and King County

    PRINCIPAL INVESTIGATOR

  • Mickey S Eisenberg, MD, PhD

    Division of Emergency Medical Services, Public Health - Seattle and King County

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Program Manager

Study Record Dates

First Submitted

September 13, 2005

First Posted

September 22, 2005

Study Start

June 1, 2004

Primary Completion

August 1, 2012

Study Completion

August 1, 2012

Last Updated

October 29, 2014

Record last verified: 2014-10

Locations

US(2)GB(1)