Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker
A Study on the Efficacy and Safety of Olmesartan Medoxomil and Its Combination With Hydrochlorothiazide Compared With an ACE Inhibitor and Its Combination With a Calcium Channel Blocker in Patients With Stage 2 Hypertension
1 other identifier
interventional
152
1 country
20
Brief Summary
A comparison of 2 different combinations of high blood pressure medications to treat hypertension
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_4 hypertension
Started Sep 2005
Shorter than P25 for phase_4 hypertension
20 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2005
CompletedFirst Submitted
Initial submission to the registry
September 9, 2005
CompletedFirst Posted
Study publicly available on registry
September 16, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2006
CompletedJanuary 18, 2012
January 1, 2012
1 year
September 9, 2005
January 16, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in systolic blood pressure from the start of the study
Secondary Outcomes (2)
Change in diastolic blood pressure from the start of the study
Percent of patients who achieve target blood pressure goals
Interventions
Eligibility Criteria
You may qualify if:
- Greater than 18 years of age
- Patients with high blood pressure
You may not qualify if:
- Hypertensive encephalopathy, stroke or transient ischemic attack within the past 6 months
- History of myocardial infarction, percutaneous transluminal coronary revascularization, coronary artery bypass graft, and/or unstable angina pectoris within the past 6 months
- Type 1 diabetes mellitus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Daiichi Sankyolead
Study Sites (20)
Unknown Facility
Mobile, Alabama, 36693, United States
Memorial Research Medical Center
Long Beach, California, 90806, United States
National Research Institute
Los Angeles, California, 90057, United States
Clinical Trials Research
Roseville, California, 95661, United States
Apex Research Institute
Santa Ana, California, 92705, United States
Orange County Research Center
Tustin, California, 92780, United States
Westlake Medical Center
Westlake Village, California, 91361, United States
Clinical Research of South Florida
Coral Gables, Florida, 33134, United States
The Greater Fort Lauderdale Heart Group Research
Fort Lauderdale, Florida, 33308, United States
SFBC International
Miami, Florida, 33142, United States
CLIRECO, Inc.
Tamarac, Florida, 33321, United States
Midwest Institute for Clinical Research
Indianapolis, Indiana, 46260, United States
Heartland Research Associates
Wichita, Kansas, 67207, United States
Androscoggin Cardiology Research
Auburn, Maine, 04210, United States
Internal Medicine Associates of Charlotte
Charlotte, North Carolina, 28211, United States
Piedmont Medical Research Associates
Winston-Salem, North Carolina, 27103, United States
The Lindner Clinical Trial Center
Cincinnati, Ohio, 45319, United States
Omega Medical Research
Warwick, Rhode Island, 02886, United States
Volunteer Research Group, University of Tennessee Med. Ctr.
Knoxville, Tennessee, 37920, United States
Punzi Medical Center
Carrollton, Texas, 75006, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 9, 2005
First Posted
September 16, 2005
Study Start
September 1, 2005
Primary Completion
September 1, 2006
Study Completion
September 1, 2006
Last Updated
January 18, 2012
Record last verified: 2012-01