NCT00184457

Brief Summary

Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they increase their maximal leg press strength, work economy, serum testosterone and quality of life. The study hypotheses are that:

  1. 1.Aerobic work capacity will increase due to increased work economy, without increases in maximal oxygen uptake.
  2. 2.Strength training will increase serum testosterone.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable heart-failure

Timeline
Completed

Started Sep 2005

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2005

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

September 15, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 16, 2005

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2007

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2007

Completed
Last Updated

January 18, 2017

Status Verified

November 1, 2011

Enrollment Period

1.6 years

First QC Date

September 15, 2005

Last Update Submit

January 16, 2017

Conditions

Heart FailureCoronary Artery Disease

Keywords

Cardiac heart failureLeg pressMaximal strength trainingSerum testosteroneWork economy

Outcome Measures

Primary Outcomes (4)

  • Maximal leg press strength

  • Work economy

  • Serum testosterone

  • Quality of life

Interventions

Strength training interventionBEHAVIORAL

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinically diagnosed coronary artery disease
  • Stable coronary artery disease
  • mm depression in ST segment during a cycling strain test
  • Between 18-70 years of age

You may not qualify if:

  • Unstable coronary artery disease
  • Other limitations to exercise than coronary artery disease
  • Participants in other study interventions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Norwegian University of Science and Technology

Trondheim, 7489, Norway

Location

Related Publications (1)

  • Karlsen T, Helgerud J, Stoylen A, Lauritsen N, Hoff J. Maximal strength training restores walking mechanical efficiency in heart patients. Int J Sports Med. 2009 May;30(5):337-42. doi: 10.1055/s-0028-1105946. Epub 2009 Feb 6.

    PMID: 19199203RESULT

MeSH Terms

Conditions

Heart FailureCoronary Artery Disease

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesCoronary DiseaseMyocardial IschemiaArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • Asbjørn Støylen, MD

    Norwegian University of Science and Technology

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2005

First Posted

September 16, 2005

Study Start

September 1, 2005

Primary Completion

April 1, 2007

Study Completion

September 1, 2007

Last Updated

January 18, 2017

Record last verified: 2011-11

Locations

NO(1)