Measuring Alterations of DNA in Human Blood

NCT00178308 | Completed

• 1 other identifier: URCC 1702
• Study Type: observational
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.

Conditions

Neoplasms

Eligibility Criteria

• Age: 21 Years - 70 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or female, age 21 to 70 years old.
• Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C.
• X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region);
• treatment could be ongoing therapy or initial therapy.

Sponsors & Collaborators

• University of Rochester: lead
• Litron Laboratories: collaborator

Study Sites (1)

University of Rochester

Rochester, New York, United States

Location

MeSH Terms

Conditions

Neoplasms

Study Officials

• Yuhchyau Chen, MD, Ph.D

  Universtiy of Rochester, Dept of Radiation Oncology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: DEFINED POPULATION
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 12, 2005
• First Posted: September 15, 2005
• Last Updated: September 11, 2006

Record last verified: 2006-09

Locations

US (1)