NCT00164424|CompletedPhase 2/3
Episodic Acyclovir Therapy for Genital Ulcers
Impact of Episodic Acyclovir Therapy on Ulcer Duration and HIV Shedding From Genital Ulcers Among Men in South Africa
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Impact of Episodic Acyclovir Therapy on Ulcer Duration and HIV Shedding From Genital Ulcers Among Men in South Africa
Sponsor study identifier
interventional
613
1 country
2
Study Start
March 2005
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
March 2009
Actual (reported)Study Completion
July 2011
Actual (reported)The purpose of this study is to determine if acyclovir episodic treatment has an effect in ulcer healing and if it should be added to the syndromic management of genital ulcer disease.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 2011
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2005
Date type not reportedThis date has not been verified as actual or estimated.
September 9, 2005
Actual (reported)September 14, 2005
Actual (reported)March 2009
Actual (reported)July 2011
Actual (reported)Ulcer healing
HIV viral load from genital ulcers
HIV viral load in semen
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Eloff Street Clinic
Johannesburg, Gauteng, South Africa
Green Door, Alexandra Health Centre
Johannesburg, Gauteng, South Africa
Paz Bailey G, Sternberg M, Lewis DA, Puren A. Acute HIV infections among men with genital ulcer disease in South Africa. J Infect Dis. 2010 Jun 15;201(12):1811-5. doi: 10.1086/652785.
Paz-Bailey G, Sternberg M, Puren AJ, Markowitz LE, Ballard R, Delany S, Hawkes S, Nwanyanwu O, Ryan C, Lewis DA. Improvement in healing and reduction in HIV shedding with episodic acyclovir therapy as part of syndromic management among men: a randomized, controlled trial. J Infect Dis. 2009 Oct 1;200(7):1039-49. doi: 10.1086/605647.
Gabriela Paz Bailey, MD
Centers for Disease Control and Prevention
David Lewis, MD
STIRC, National Institute for Communicable Diseases (NICD), South Africa
613 participants (actual enrollment reported by the registry).
First Submitted
September 9, 2005
First Posted
September 14, 2005
Study Start
March 2005
Date type not reportedThis date has not been verified as actual or estimated.
Acyclovir to Treat Patients Co-infected With HIV and Herpes Viruses in Uganda
Contact the study team to confirm eligibility.
Primary Completion
March 2009
Actual (reported)Study Completion
July 2011
Actual (reported)Last Updated
September 11, 2012
Record last verified: 2012-09
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Source: ClinicalTrials.gov.
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