NCT00155493

Brief Summary

Periorbital rejuvenation has been an issue of great interest in plastic surgery. Adipose tissue plays an important role in the periorbital anatomy, and has a great impact on the aging process of the region. We believe age-related atrophy of the facial adipose tissue may be related to the decreased proliferation and differentiation capability of the preadipocytes (adipose precursor cells).

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Jan 2006

Shorter than P25 for phase_1

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 9, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 12, 2005

Completed
4 months until next milestone

Study Start

First participant enrolled

January 1, 2006

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2006

Completed
Last Updated

September 12, 2005

Status Verified

June 1, 2005

First QC Date

September 9, 2005

Last Update Submit

September 9, 2005

Conditions

Aging

Outcome Measures

Primary Outcomes (1)

  • preadipocyte proportion in aged versus young group

Interventions

obtain surgical specimen for analysisPROCEDURE

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients receiving lower blepharoplasty

You may not qualify if:

  • patients who do not require fat removal

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Yueh-Bih Tang, M.D. Ph.D.

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yueh-Bih Tang, M.D. Ph.D.

CONTACT

886-2-23123456phoebe@ha.mc.ntu.edu.tw

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
ECT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 9, 2005

First Posted

September 12, 2005

Study Start

January 1, 2006

Study Completion

August 1, 2006

Last Updated

September 12, 2005

Record last verified: 2005-06