NCT00154661

Brief Summary

we hypothesize that PTX might be effective in lowering proteinuria by modulating renal MCP-1 production in human glomerulonephritis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2000

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2000

Completed
1.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2001

Completed
4.3 years until next milestone

First Submitted

Initial submission to the registry

September 8, 2005

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 12, 2005

Completed
Last Updated

September 12, 2005

Status Verified

June 1, 2001

First QC Date

September 8, 2005

Last Update Submit

September 8, 2005

Conditions

Primary Glomerulonephritis

Keywords

glomerulonephritis

Outcome Measures

Primary Outcomes (1)

  • proteinuria

Secondary Outcomes (1)

  • inflammatory mediators

Interventions

pentoxifyllineDRUG

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • glomerular diseases with subnephrotic proteinuria

You may not qualify if:

  • DM, hepatitis, systemic immunologic renal diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yung-Ming Chen

Taipei, 100, Taiwan

Location

MeSH Terms

Conditions

Glomerulonephritis

Interventions

Pentoxifylline

Condition Hierarchy (Ancestors)

NephritisKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

TheobromineXanthinesPurinonesPurinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-RingHeterocyclic Compounds

Study Officials

  • Pan-Chyr Yang

    Professor and vice-Dean

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 8, 2005

First Posted

September 12, 2005

Study Start

January 1, 2000

Study Completion

June 1, 2001

Last Updated

September 12, 2005

Record last verified: 2001-06

Locations

TW(1)