Success Metrics

Clinical Success Rate
85.3%

Based on 58 completed trials

Completion Rate
85%(58/68)
Active Trials
12(11%)
Results Posted
31%(18 trials)
Terminated
10(9%)

Phase Distribution

Ph phase_4
14
12%
Ph phase_1
12
11%
Ph phase_3
16
14%
Ph phase_2
40
35%
Ph early_phase_1
7
6%
Ph not_applicable
22
19%

Phase Distribution

19

Early Stage

40

Mid Stage

30

Late Stage

Phase Distribution111 total trials
Early Phase 1First-in-human
7(6.3%)
Phase 1Safety & dosage
12(10.8%)
Phase 2Efficacy & side effects
40(36.0%)
Phase 3Large-scale testing
16(14.4%)
Phase 4Post-market surveillance
14(12.6%)
N/ANon-phased studies
22(19.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.7%

58 of 71 finished

Non-Completion Rate

18.3%

13 ended early

Currently Active

12

trials recruiting

Total Trials

114

all time

Status Distribution
Active(16)
Completed(58)
Terminated(13)
Other(27)

Detailed Status

Completed58
unknown27
Terminated10
Recruiting9
Not yet recruiting4
Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials
114
Active
12
Success Rate
85.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (6.3%)
Phase 112 (10.8%)
Phase 240 (36.0%)
Phase 316 (14.4%)
Phase 414 (12.6%)
N/A22 (19.8%)

Trials by Status

completed5851%
active_not_recruiting33%
unknown2724%
not_yet_recruiting44%
terminated109%
recruiting98%
withdrawn33%

Recent Activity

Clinical Trials (114)

Showing 20 of 114 trialsScroll for more
NCT07561801Not Applicable

Pentoxifylline for Prevention of Contrast Induced Nephropathy in Chronic Kidney Diseased Patients in Intensive Care Unit

Completed
NCT03040778Phase 3

Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ)

Active Not Recruiting
NCT07349472Phase 2

Pentoxifylline in Patients With Ulcerative Colitis

Recruiting
NCT03625648Phase 4

Pentoxifylline in Diabetic Kidney Disease

Active Not Recruiting
NCT06634056Phase 2

Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients Undergoing Chemoradiation

Not Yet Recruiting
NCT05513560Phase 2

RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine

Completed
NCT06494111Phase 2

Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)

Recruiting
NCT06912763Phase 2

Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

Recruiting
NCT07315139Not Applicable

Pentoxifylline on Inflammatory Markers in Non-Diabetic Chronic Kidney Disease Patients

Completed
NCT07086794Early Phase 1

Cocaine and Pentoxifylline (BED IN 47)

Recruiting
NCT06998628Phase 2

Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis

Recruiting
NCT05635370

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Pentoxifylline Versus Cilostazol

Completed
NCT06944704Phase 2

Evaluation of Efficacy, Safety and Molecular Mechanism of Pentoxifylline Supplementation in Patients With Hepatic and Obstructive Jaundice

Completed
NCT07088328Not Applicable

Nephroprotection Following Perinatal Asphyxia: Randomized Controlled Trial

Not Yet Recruiting
NCT06087237Phase 2

The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery

Completed
NCT06332612Phase 1

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial

Completed
NCT06823362Phase 4

Bioequivalence Study of Pentoxifylline 400 Mg in Healthy Subjects Under Fasting and Fed Conditions

Not Yet Recruiting
NCT02592863Not Applicable

Trental for the Treatment of Vertigo/Dizziness/Imbalance

Terminated
NCT06562998Not Applicable

Pentoxifylline Role Against Chemotherapy-induced Neuropathy

Completed
NCT04152980Phase 3

Pentoxifylline Dose Optimization in Neonatal Sepsis

Completed

Drug Details

Intervention Type
DRUG
Total Trials
114