A Randomized, Phase 3, Double Blind, Multicentre Trial, Evaluating the Effect of Pioglitazone Versus Placebo on Change in Lipoatrophy in HIV- 1 Infected Patients Treated With Stable Antiretroviral Therapy for at Least 6 Months.ANRS 113 LIPIOT Study
Sponsor study identifier
interventional
130
1 country
1
Study Start
February 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
October 2004
Date type not reportedThis date has not been verified as actual or estimated.
The aim of this randomized study is to compare the effect of pioglitazone versus placebo on change in limb fat in HIV 1-infected patients treated with antiretroviral therapy for at least 6 months and with clinical lipoatrophy.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 2004
Date type not reportedThis date has not been verified as actual or estimated.
Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 2003
Date type not reportedThis date has not been verified as actual or estimated.
October 2004
Date type not reportedThis date has not been verified as actual or estimated.
September 7, 2005
Actual (reported)September 8, 2005
Actual (reported)Evolution from inclusion to week 48 of limb fat using DEXA Scan (Dual Energy X-ray Absorptiometry)
Changes from inclusion to week 48:
Lipid profile and the glucidic metabolism
SAT/TAT and VAT/TAT ratios evaluated with scanner
X ray of L4
Anthropometric measurements and the quality of life (WHO-QOL-HIV BREF)
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Service des Maladies Infectieuses et Tropicales, Hopital Tenon
Paris, 75020, France
Slama L, Lanoy E, Valantin MA, Bastard JP, Chermak A, Boutekatjirt A, William-Faltaos D, Billaud E, Molina JM, Capeau J, Costagliola D, Rozenbaum W. Effect of pioglitazone on HIV-1-related lipodystrophy: a randomized double-blind placebo-controlled trial (ANRS 113). Antivir Ther. 2008;13(1):67-76.
Willy Rozenbaum, MD
Hopital Tenon Paris
Dominique Costagliola
INSERM U 720
First Submitted
September 7, 2005
First Posted
September 8, 2005
Study Start
February 2003
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
October 2004
Date type not reportedContact the study team to confirm eligibility.
This date has not been verified as actual or estimated.
Last Updated
October 20, 2005
Record last verified: 2005-09
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: