Short Term Outcomes of Children With Acute Respiratory Distress Syndrome
1 other identifier
observational
N/A
1 country
1
Brief Summary
The study is a chart review of all children admitted over a two year period with the diagnosis of acute respiratory distress syndrome. Short term outcomes, such as mortality, length of ventilation and length of stay, will be reviewed. Factors that impact these outcomes will also be reviewed.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Sep 2004
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2004
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2005
CompletedFirst Submitted
Initial submission to the registry
September 1, 2005
CompletedFirst Posted
Study publicly available on registry
September 2, 2005
CompletedSeptember 2, 2005
September 1, 2004
September 1, 2005
September 1, 2005
Conditions
Eligibility Criteria
You may qualify if:
- Rapidly progressive respiratory failure,
- Severe hypoxemia (PaO2/FiO2 \< 200),
- Evidence of bilateral pulmonary infiltrate on chest radiography
- years of age
You may not qualify if:
- Heart failure
- Cardiac shunt present
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Columbus Children's Hospital
Columbus, Ohio, 43015, United States
Related Publications (7)
Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 1994 Mar;149(3 Pt 1):818-24. doi: 10.1164/ajrccm.149.3.7509706.
PMID: 7509706BACKGROUNDDavis SL, Furman DP, Costarino AT Jr. Adult respiratory distress syndrome in children: associated disease, clinical course, and predictors of death. J Pediatr. 1993 Jul;123(1):35-45. doi: 10.1016/s0022-3476(05)81534-3.
PMID: 8320623BACKGROUNDTimmons OD, Havens PL, Fackler JC. Predicting death in pediatric patients with acute respiratory failure. Pediatric Critical Care Study Group. Extracorporeal Life Support Organization. Chest. 1995 Sep;108(3):789-97. doi: 10.1378/chest.108.3.789.
PMID: 7656635BACKGROUNDKatz R. Adult respiratory distress syndrome in children. Clin Chest Med. 1987 Dec;8(4):635-9.
PMID: 3322648BACKGROUNDTimmons OD, Dean JM, Vernon DD. Mortality rates and prognostic variables in children with adult respiratory distress syndrome. J Pediatr. 1991 Dec;119(6):896-9. doi: 10.1016/s0022-3476(05)83039-2.
PMID: 1960603BACKGROUNDMilberg JA, Davis DR, Steinberg KP, Hudson LD. Improved survival of patients with acute respiratory distress syndrome (ARDS): 1983-1993. JAMA. 1995 Jan 25;273(4):306-9.
PMID: 7815658BACKGROUNDAcute Respiratory Distress Syndrome Network; Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000 May 4;342(18):1301-8. doi: 10.1056/NEJM200005043421801.
PMID: 10793162BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Onsy Ayad, MD
Nationwide Children's Hospital
Study Design
- Study Type
- observational
- Observational Model
- DEFINED POPULATION
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 1, 2005
First Posted
September 2, 2005
Study Start
September 1, 2004
Study Completion
August 1, 2005
Last Updated
September 2, 2005
Record last verified: 2004-09