Urinary Schistosomiasis Infection

NCT00138450 | Completed

• 1 other identifier: 01-588
• Study Type: observational
• Target: 4,400
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine what causes some people to become sick, and others not, when they are infected with the parasite Schistosoma haematobium, also known as Bilharzia. This is an infection of the urinary tract blood vessels and can cause serious disease. Approximately 4400 adults and children of any age will participate in this study. They must be residents of the Msambweni Area, Kwale District, Coast Province, Kenya, where infection with S. haematobium parasites are common. To find out if people are infected, they will first provide 1 or more urine samples for a microscope examination to detect if the S. haematobium parasites are present in the body. Volunteers then will be examined by ultrasound to see if they have kidney or bladder disease. (Ultrasound examination is the use of a non-painful machine that uses sound waves to examine the condition of the internal organs.) Treatment with the drug praziquantel will be offered if S. haematobium infection is found.

Conditions

Diseases of the Urinary System; Schistosomiasis Haematobia

Keywords

Schistosomiasis, S. haematobium, morbidity, Kenya

Eligibility Criteria

• Age: Up to 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Kenyan residents, newborn to adult, either male or female.
• Residence in areas of Kwale District endemic for Schistosoma haematobium

Sponsors & Collaborators

• National Institute of Allergy and Infectious Diseases (NIAID): lead

Study Sites (1)

KEMRI Centre for Geographic Medicine Research

Kilifi, Kenya

Location

MeSH Terms

Conditions

Urologic Diseases; Schistosomiasis haematobia; Schistosomiasis

Condition Hierarchy (Ancestors)

Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Trematode Infections; Helminthiasis; Parasitic Diseases; Infections; Urinary Tract Infections; Vector Borne Diseases

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: NIH

Study Record Dates

• First Submitted: August 26, 2005
• First Posted: August 30, 2005
• Study Completion: November 1, 2004
• Last Updated: January 30, 2019

Record last verified: 2007-03

Locations

KE (1)