NCT00137306|CompletedPhase 4
Facilitating the Adoption of Evidence-Based Depression Management in Substance Use Treatment Programs
Translating Depression Guidelines Into Substance Abuse Treatment
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Translating Depression Guidelines Into Substance Abuse Treatment
Sponsor study identifier
interventional
300
1 country
5
Study Start
January 2004
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
October 2006
Actual (reported)Study Completion
October 2006
Actual (reported)Comorbid depression has been consistently linked to worse outcomes for patients in substance abuse treatment programs. Practice guidelines recommend pharmacotherapy for comorbid depression if symptoms persist after a 4-week "wash-out" period for detoxification (e.g., Veterans Health Administration; American Psychiatric Association). Medications may be considered earlier if a patient has current symptoms and a history of major depressive disorder (MDD) during periods of sobriety. Current efficacy data suggest that antidepressant medication can improve both depression and substance use outcomes among comorbid patients Guideline-concordant use of antidepressant medication for persons with comorbid substance use and depressive disorders, however, is not routine in many VA substance abuse treatment settings.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 2006
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2004
Date type not reportedThis date has not been verified as actual or estimated.
August 25, 2005
Actual (reported)August 29, 2005
Actual (reported)October 2006
Actual (reported)October 2006
Actual (reported)Program: extent, quality of adoption of protocolPatient: scores on-depression, substance use, and functioning scales
Programs: Staff satisfaction with protocol/intervention Patients: medication adherence
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Central Arkansas Veterans Healthcare System Eugene J. Towbin Healthcare Center, Little Rock, AR
No. Little Rock, Arkansas, 72114-1706, United States
Southeast Louisiana Veterans Health Care System, New Orleans, LA
New Orleans, Louisiana, 70112, United States
VA Gulf Coast Veterans Health Care System
Biloxi, Mississippi, 39531, United States
G.V. (Sonny) Montgomery VA Medical Center, Jackson, MS
Jackson, Mississippi, 39216, United States
Oklahoma City, OK
Oklahoma City, Oklahoma, 73104, United States
Curran GM, Mukherjee S, Allee E, Owen RR. A process for developing an implementation intervention: QUERI Series. Implement Sci. 2008 Mar 19;3:17. doi: 10.1186/1748-5908-3-17.
Curran GM, Kirchner JE, Worley M, Rookey C, Booth BM. Depressive symptomatology and early attrition from intensive outpatient substance use treatment. J Behav Health Serv Res. 2002 May;29(2):138-43. doi: 10.1007/BF02287700.
Geoffrey M. Curran, PhD
Central Arkansas Veterans Healthcare System Eugene J. Towbin Healthcare Center, Little Rock, AR
First Submitted
August 25, 2005
First Posted
August 29, 2005
Study Start
January 2004
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
October 2006
Actual (reported)Methamphetamine Abuse Treatment in Patients With AIDS - 1
Study Completion
October 2006
Actual (reported)Last Updated
April 7, 2015
Record last verified: 2007-02
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Source: ClinicalTrials.gov.
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