NCT00015301

Brief Summary

The purpose of this study is to evaluate PET methodology to study in vivo synaptic dopamine release.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Dec 2003

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 18, 2001

Completed
Same day until next milestone

First Posted

Study publicly available on registry

April 18, 2001

Completed
2.6 years until next milestone

Study Start

First participant enrolled

December 1, 2003

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2005

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2005

Completed
Last Updated

February 24, 2017

Status Verified

December 1, 2002

Enrollment Period

1.5 years

First QC Date

April 18, 2001

Last Update Submit

February 23, 2017

Conditions

Cocaine-Related DisordersSubstance-Related Disorders

Outcome Measures

Primary Outcomes (1)

  • Dopamine receptor availability

Interventions

MethylphenidateDRUG

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy normals

You may not qualify if:

  • History of head trauma or loss of consciousness. Significant medical history. History of seizures.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York MDRU

New York, New York, 10010, United States

Location

MeSH Terms

Conditions

Cocaine-Related DisordersSubstance-Related Disorders

Interventions

Methylphenidate

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

PhenylacetatesAcids, CarbocyclicCarboxylic AcidsOrganic ChemicalsPiperidinesHeterocyclic Compounds, 1-RingHeterocyclic Compounds

Study Officials

  • John Rotrosen, M.D.

    New York MDRU

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 4
Masking
DOUBLE
Purpose
DIAGNOSTIC
Sponsor Type
NIH

Study Record Dates

First Submitted

April 18, 2001

First Posted

April 18, 2001

Study Start

December 1, 2003

Primary Completion

June 1, 2005

Study Completion

August 1, 2005

Last Updated

February 24, 2017

Record last verified: 2002-12

Locations

US(1)