NCT00132223

Brief Summary

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents. Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients. All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s. The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for phase_4

Timeline
Completed

Started Apr 2005

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2005

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 18, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 19, 2005

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2005

Completed
Last Updated

April 12, 2006

Status Verified

April 1, 2006

First QC Date

August 18, 2005

Last Update Submit

April 11, 2006

Conditions

HeadacheEpilepsyDizziness

Keywords

magnetic imagingangiographycontrast agentsignal/noise ratiocontrast/noise ratiovessel

Outcome Measures

Primary Outcomes (1)

  • intensity of vessels, muscle, air

Secondary Outcomes (2)

  • signal/noise ratio

  • contrast/nose ratio

Interventions

Contrast agentDRUG

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Headache
  • Epilepsia
  • Dizziness

You may not qualify if:

  • Pregnancy
  • Metal implants (e.g. pacemaker)
  • Contraindication for contrast agent
  • Multiple allergies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Muenster, Dept. of Clinical Radiology

Münster, 48129, Germany

RECRUITING

MeSH Terms

Conditions

HeadacheEpilepsyDizziness

Interventions

Contrast Media

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesSensation Disorders

Intervention Hierarchy (Ancestors)

Diagnostic Uses of ChemicalsPharmacologic ActionsChemical Actions and UsesSpecialty Uses of Chemicals

Study Officials

  • Bernd Tombach, MD

    University of Muenster, Dept. of Clinical Radiology

    STUDY CHAIR

Central Study Contacts

Boris Buerke, MD

CONTACT

00492518345123buerkeb@uni-muenster.de

Bernd Tombach, MD

CONTACT

00492518345123tombach@uni-muenster.de

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
SINGLE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 18, 2005

First Posted

August 19, 2005

Study Start

April 1, 2005

Study Completion

December 1, 2005

Last Updated

April 12, 2006

Record last verified: 2006-04

Locations

DE(1)