NCT00131521

Completed

Comparison of Different Mucoactive Agents for the Care of th...

The University of Texas Health Science Center at San Antonio Source

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Other study identifiers

Sponsor study identifier

034-1502-320

Study Type

interventional

Estimated enrollment

260

Locations

1 country

Sites

1

Timeline

Study Start

January 2005

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

Not reported

Date not reported

Study Completion

December 2007

Actual (reported)

Brief Summary

This study compares N-acetylcysteine (mucomyst) and sodium chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the surgical trauma intensive care unit (STICU).

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Estimated enrollment: 260 participants
Study completion date: December 2007
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
January 2005
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
August 17, 2005
Actual (reported)
First Posted
August 18, 2005
Actual (reported)
Study Completion
December 2007
Actual (reported)

Last Updated: June 23, 2009
Status Verified: June 2009
Last Update Submitted: June 20, 2009

Conditions

Intubation Mucus Obstruction

Keywords

mucus obstruction, ventilator management

Outcome Measures

Primary Outcomes (1)

prevention of pulmonary mucus obstruction

Secondary Outcomes (1)

days of mechanical ventilation

Interventions

mucomystDrug

sodium chloride (saline)Drug

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Intubated and admitted to the Surgical Trauma Intensive Care Unit (STICU)
Subjects must be eligible to start treatment within 24 hours of their initial intubation

You may not qualify if:

Sponsors & Collaborators

The University of Texas Health Science Center at San Antonio
Otherlead

Study Sites (1)

Univesity Hospital

San Antonio, Texas, 78229, United States

MeSH Terms

Interventions

AcetylcysteineSodium Chloride

Intervention Hierarchy (Ancestors)

CysteineAmino Acids, SulfurSulfur CompoundsOrganic ChemicalsAmino AcidsAmino Acids, Peptides, and ProteinsChloridesHydrochloric AcidChlorine CompoundsInorganic ChemicalsSodium Compounds

Study Officials

John G. Myers, M.D.
The University of Texas Health Science Center at San Antonio
PRINCIPAL INVESTIGATOR

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: DOUBLE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER

Study Record Dates

First Submitted

August 17, 2005

First Posted

August 18, 2005

Study Start

January 2005

Date type not reported

This date has not been verified as actual or estimated.

Study Completion

December 2007

Actual (reported)

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NCT03503279

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NCT07483164

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Not ApplicableEnrolling By Invitation

Patient anticipated to be extubated within 24 hours following STICU admission
Hypersensitivity to acetylcysteine.
Pregnancy

Contact the study team to confirm eligibility.

Last Updated

June 23, 2009

Record last verified: 2009-06

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

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Registry identifier: NCT00131521
Data provider: ClinicalTrials.gov
Source updated: 2009-06-23
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:23:36 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

Source record

Locations