NCT00128336

Brief Summary

The purpose of this trial is to determine the most cost effective programme for overweight and obese individuals to maintain weight loss over a 2 year period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P25-P50 for phase_3 obesity

Timeline
Completed

Started May 2004

Typical duration for phase_3 obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2004

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

August 8, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 9, 2005

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2006

Completed
Last Updated

May 16, 2016

Status Verified

May 1, 2016

Enrollment Period

2.4 years

First QC Date

August 8, 2005

Last Update Submit

May 12, 2016

Conditions

Keywords

WeightDietexercisemaintenance

Outcome Measures

Primary Outcomes (1)

  • Weight

    2 years

Secondary Outcomes (6)

  • Body composition

    2 years

  • Waist circumference and blood pressure

    2 years

  • Lipid profile and glucose and insulin

    2 years

  • Dietary intake

    2 years

  • Physical fitness

    2 years

  • +1 more secondary outcomes

Study Arms (4)

Nurse support

ACTIVE COMPARATOR
Behavioral: Lifestyle: diet and exercise intervention

Intensive support

EXPERIMENTAL
Behavioral: Lifestyle: diet and exercise intervention

High carbohydrate diet

ACTIVE COMPARATOR
Behavioral: Lifestyle: diet and exercise intervention

High mono-unsaturated fat diet

EXPERIMENTAL
Behavioral: Lifestyle: diet and exercise intervention

Interventions

High carbohydrate dietHigh mono-unsaturated fat dietIntensive supportNurse support

Eligibility Criteria

Age25 Years - 70 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Female participants
  • Aged 25 to 70
  • Those who have intentionally lost more than or equal to 5% of initial body weight in the previous 6 months will be recruited
  • Objective evidence that volunteers were overweight or obese and have lost weight will be obtained from doctors records

You may not qualify if:

  • Presence of major illness including cancers
  • Established cardiovascular disease or stroke
  • Diabetes
  • Gestational diabetes
  • Renal disease
  • Malabsorption disorders
  • Thyroid disorders
  • Major psychiatric disorders
  • Taking weight loss medication or medications known to cause weight gain
  • Planning a pregnancy in the next 2 years
  • Those who do not intend to be in the area for the next 2 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Human Nutrition, University of Otago

Dunedin, 9001, New Zealand

Location

Related Publications (1)

  • Dale KS, McAuley KA, Taylor RW, Williams SM, Farmer VL, Hansen P, Vorgers SM, Chisholm AW, Mann JI. Determining optimal approaches for weight maintenance: a randomized controlled trial. CMAJ. 2009 May 12;180(10):E39-46. doi: 10.1503/cmaj.080974.

MeSH Terms

Conditions

ObesityDiabetes Mellitus, Type 2Body WeightMotor Activity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesEndocrine System DiseasesBehavior

Study Officials

  • Kelly S Whiteford, MSc (Dist)

    University of Otago

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD student

Study Record Dates

First Submitted

August 8, 2005

First Posted

August 9, 2005

Study Start

May 1, 2004

Primary Completion

October 1, 2006

Study Completion

October 1, 2006

Last Updated

May 16, 2016

Record last verified: 2016-05

Locations