NCT00125632

Brief Summary

The purpose of this study is to measure the effectiveness of a newly-designed oculomotor training program for patients with age-related macular degeneration.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2005

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 28, 2005

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 1, 2005

Completed
Same day until next milestone

Study Start

First participant enrolled

August 1, 2005

Completed
2.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2008

Completed
Last Updated

February 5, 2009

Status Verified

December 1, 2006

First QC Date

July 28, 2005

Last Update Submit

February 3, 2009

Conditions

Age Related MaculopathyRetinal Degeneration

Keywords

ReadingRehabilitationTreatment OutcomesLow vision

Outcome Measures

Primary Outcomes (1)

  • Participants will be given the following assessment tests at 4 different times during the assessment (at baseline, after 6 weeks, after 12 weeks, and after 18 weeks): eye tracking measures, daily performance measures and reading measures.

Interventions

Eccentric Viewing Training for ReadingPROCEDURE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with a diagnosis of AMD
  • An established preferred retinal locus
  • Visual acuity of less than or equal to 20/70 and greater than or equal to 20/400 (in the better eye)

You may not qualify if:

  • Those with other major ophthalmologic and neurologic disease; choroidal neovascularization ("wet" AMD); moderate to severe media opacities; and cognitive impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jesse Brown VA Medical Center

Chicago, Illinois, 60612, United States

Location

Related Publications (3)

  • Szlyk JP, Paliga J, Seiple W, Rabb MF. Comprehensive functional vision assessment of patients with North Carolina macular dystrophy (MCDR1). Retina. 2005 Jun;25(4):489-97. doi: 10.1097/00006982-200506000-00015.

    PMID: 15933597BACKGROUND

  • Grant P, Seiple W, Szlyk JP. Effect of depression on actual and perceived effects of reading rehabilitation for people with central vision loss. J Rehabil Res Dev. 2011;48(9):1101-8. doi: 10.1682/jrrd.2010.05.0080.

    PMID: 22234714DERIVED

  • Seiple W, Grant P, Szlyk JP. Reading rehabilitation of individuals with AMD: relative effectiveness of training approaches. Invest Ophthalmol Vis Sci. 2011 May 5;52(6):2938-44. doi: 10.1167/iovs.10-6137.

    PMID: 21296824DERIVED

Related Links

MeSH Terms

Conditions

Macular DegenerationRetinal DegenerationVision, Low

Condition Hierarchy (Ancestors)

Retinal DiseasesEye DiseasesEye Diseases, HereditaryVision DisordersSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Janet P Szlyk, Ph.D.

    Research & Development Service 151, Jesse Brown VA Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
DOUBLE
Intervention Model
CROSSOVER
Sponsor Type
FED

Study Record Dates

First Submitted

July 28, 2005

First Posted

August 1, 2005

Study Start

August 1, 2005

Study Completion

May 1, 2008

Last Updated

February 5, 2009

Record last verified: 2006-12

Locations

US(1)