Retinal Degeneration
67
10
15
30
Key Insights
Highlights
Success Rate
81% trial completion
Published Results
11 trials with published results (16%)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 72/100
10.4%
7 terminated out of 67 trials
81.1%
-5.4% vs benchmark
4%
3 trials in Phase 3/4
37%
11 of 30 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 30 completed trials
Clinical Trials (67)
Natural History of Eye Diseases Related to ABCA4 Mutations
Cell Collection to Study Eye Diseases
Oral Metformin for Treatment of ABCA4 Retinopathy
Rod and Cone Mediated Function in Retinal Disease
MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)
A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)
First-in-Human, Dose Escalation Trial of AXV-101 in BBS1-Related Retinal Degeneration
Multicenter Study of Transcranial Magnetic Stimulation on Vision Restoration
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD
SGLT2 Inhibitors in Geographic Atrophy
A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001
High Resolution, High-speed Multimodal Ophthalmic Imaging
Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)
Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study
Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking Ofatumumab
A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema
Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis
Adaptive Optics Imaging of Outer Retinal Diseases
A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal Injection