NCT00124319

Brief Summary

The anterior cruciate ligament (ACL) is located inside the knee joint and provides stability to the knee. ACL injuries occur more frequently in women than men; the reason for this is unknown. The purpose of this study is to determine gender-specific anatomical, hormonal, and demographic risk factors for ACL injury. This observational cohort study will only enroll incoming cadets at the U.S. Naval, Air Force, or Military Academies. Study hypothesis: Human movement factors, including key kinetics and kinematics of the knee during a jump-landing task, are associated with the rate of ACL injury.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,800

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2005

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2005

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

July 25, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 27, 2005

Completed
5.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2011

Completed
Last Updated

October 5, 2011

Status Verified

May 1, 2009

Enrollment Period

5.8 years

First QC Date

July 25, 2005

Last Update Submit

October 3, 2011

Conditions

Knee InjuriesAthletic Injuries

Keywords

BiomechanicsNeuromuscularLower limbInjuryACLAnterior Cruciate Ligament injury

Study Arms (1)

1

Incoming cadets at the U.S. Naval, Air Force, or Military Academies

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Incoming cadets at the U.S. Naval, Air Force, or Military Academies

You may qualify if:

  • Incoming cadet at the U.S. Naval, Air Force, or Military Academies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

U.S. Air Force Academy

Colorado Springs, Colorado, 80840, United States

Location

U.S. Naval Academy

Annapolis, Maryland, 21402-5000, United States

Location

U.S. Military Academy

West Point, New York, 10996, United States

Location

MeSH Terms

Conditions

Knee InjuriesAthletic InjuriesWounds and InjuriesAnterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Leg Injuries

Study Officials

  • Stephen W. Marshall, PhD

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor of Epidemiology

Study Record Dates

First Submitted

July 25, 2005

First Posted

July 27, 2005

Study Start

June 1, 2005

Primary Completion

March 1, 2011

Study Completion

March 1, 2011

Last Updated

October 5, 2011

Record last verified: 2009-05

Locations

US(3)