Clinical Indicators of Radiographic Findings in Patients With Suspected Community-Acquired Pneumonia

NCT00118651 | Completed

• 1 other identifier: FDG20040023H
• Study Type: observational
• Target: 350
• Locations: 1 country
• Sites: 1

Brief Summary

This is a study involving the emergency department and outpatient clinics of the David Grant United States Air Force (USAF) Medical Center, a tertiary care facility. Patients 18 years of age or older with acute respiratory symptoms and positive or equivocal chest radiographs from October 1, 2004 through May 31, 2005 will be included as positive cases. Controls will be randomly selected from a review of negative chest radiograph reports with a clinical history of an acute respiratory illness over the same time period. Once patients are appropriately identified as control or cases, outpatient charts will be reviewed to gather data on six clinical indicators. Sensitivities and specificities will be calculated for each clinical indicator, to determine which patients require chest radiographs in the setting of suspected community acquired pneumonia (CAP)

Conditions

Pneumonia

Keywords

pneumonia; chest x-ray; respiratory infection; prediction rule; thoracic imaging

Study Arms (2)

Positive cases

Positive radiographic findings were defined as the presence of a new air space opacities in the setting of acute respiratory symptoms. Patients with equivocal radiographic findings interpreted as "possible pneumonia" were considered positive cases

Control

Acute respiratory symptoms, negative chest radiographs, and a date of birth within five years of that of the positive case

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All adult patients (18 years of age or older) with acute respiratory symptoms and positive chest radiographs from October 2004 through April 2005 were enrolled as positive cases with an equal number of controls with acute respiratory symptoms but negative radiographs; controls were matched by age and date of radiograph

You may qualify if:

• years of age or older
• acute respiratory symptoms
• positive chest radiographs
• patients from outpatient clinics and the emergency department

You may not qualify if:

• under the age of 18
• suspected hospital-acquired pneumonia (positive radiographs within 10 days of hospital discharge)
• suspected aspiration pneumonia

Sponsors & Collaborators

• David Grant U.S. Air Force Medical Center: lead

Study Sites (1)

David Grant USAF Medical Center

Travis Air Force Base, California, 94535, United States

Location

MeSH Terms

Conditions

Pneumonia; Respiratory Tract Infections

Condition Hierarchy (Ancestors)

Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• William T. O'Brien, D.O.

  David Grant USAF Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: FED
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 1, 2005
• First Posted: July 12, 2005
• Study Start: October 1, 2004
• Primary Completion: April 1, 2005
• Study Completion: April 1, 2005
• Last Updated: April 17, 2020

Record last verified: 2020-04

Locations

US (1)