NCT00112255

Brief Summary

The purpose of this study was to compare the effectiveness of partner notification by general practice nurses with referral to a specialist clinic for people with genital chlamydia diagnosed in a community setting. We hypothesised that referral to a specialist would be more effective in ensuring treatment of the sexual partners of infected people than the simpler nurse-led strategy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
214

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started Mar 2001

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2001

Completed
1.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2002

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

May 31, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 1, 2005

Completed
Last Updated

January 17, 2018

Status Verified

January 1, 2018

First QC Date

May 31, 2005

Last Update Submit

January 16, 2018

Conditions

Keywords

Chlamydia trachomatisChlamydia infectionsRandomized controlled trialsContact tracingFamily practice

Outcome Measures

Primary Outcomes (2)

  • Percentage of index cases with at least one sexual partner treated

  • Number of sexual partners per index case treated

Secondary Outcomes (3)

  • Number of sexual partners per index case elicited during sexual history taking

  • Positive chlamydia test result six weeks after treatment

  • Adherence to advice to abstain from sexual intercourse until both partners completed treatment

Interventions

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Chlamydia trachomatis diagnosed through a population-based screening study
  • Chlamydia test result received at patient's general practice
  • Chlamydia cases diagnosed in general practice

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Chlamydia Screening Studies (ClaSS) project general practices

Bristol, Avon, BS8 2PR, United Kingdom

Location

Chlamydia Screening Studies (ClaSS) project general practices

Birmingham, West Midlands, B15 2TT, United Kingdom

Location

Related Publications (2)

  • Low N, McCarthy A, Macleod J, Salisbury C, Horner PJ, Roberts TE, Campbell R, Herring A, Skidmore S, Sanford E, Sterne JA, Davey Smith G, Graham A, Huengsberg M, Ross J, Egger M. The chlamydia screening studies: rationale and design. Sex Transm Infect. 2004 Oct;80(5):342-8. doi: 10.1136/sti.2003.006197.

    PMID: 15459400BACKGROUND
  • Low N, McCarthy A, Roberts TE, Huengsberg M, Sanford E, Sterne JA, Macleod J, Salisbury C, Pye K, Holloway A, Morcom A, Patel R, Robinson SM, Horner P, Barton PM, Egger M. Partner notification of chlamydia infection in primary care: randomised controlled trial and analysis of resource use. BMJ. 2006 Jan 7;332(7532):14-9. doi: 10.1136/bmj.38678.405370.7C. Epub 2005 Dec 15.

MeSH Terms

Conditions

Chlamydia Infections

Condition Hierarchy (Ancestors)

Chlamydiaceae InfectionsGram-Negative Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfectionsSexually Transmitted Diseases, BacterialSexually Transmitted DiseasesCommunicable DiseasesGenital DiseasesUrogenital Diseases

Study Officials

  • Nicola Low, MFPH

    Chlamydia Screening Studies (ClaSS) Project General Practices

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 31, 2005

First Posted

June 1, 2005

Study Start

March 1, 2001

Study Completion

December 1, 2002

Last Updated

January 17, 2018

Record last verified: 2018-01

Locations