Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse
Integrated CBT for Substance Use and Depressive Disorders
1 other identifier
interventional
N/A
1 country
1
Brief Summary
The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use disorders.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2004
CompletedFirst Submitted
Initial submission to the registry
April 14, 2005
CompletedFirst Posted
Study publicly available on registry
April 15, 2005
CompletedMarch 6, 2009
March 1, 2009
April 14, 2005
March 4, 2009
Conditions
Keywords
Study Arms (2)
1
EXPERIMENTALIntegrated Cognitive Behavioral Therapy
2
EXPERIMENTALTwelve Step Facilitation Therapy
Interventions
Eligibility Criteria
You may qualify if:
- Individuals diagnosed with one or more substance use disorders (alcohol, cannabis, and or stimulant abuse/dependence) and an independent co-occurring depressive disorder (major depression or dysthymia) will be included.
You may not qualify if:
- Individuals with substance induced mood disorders and individuals experiencing persistent psychotic symptoms.
- Those with life threatening or unstable medical illness, neurological disorders, or inability to read will be excluded.
- Individuals currently prescribed steroids, disulfiram, or long acting benzodiazepines will be excluded.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
VA San Diego Healthcare System, San Diego
San Diego, California, 92161, United States
Related Publications (4)
Worley MJ, Tate SR, Granholm E, Brown SA. Mediated and moderated effects of neurocognitive impairment on outcomes of treatment for substance dependence and major depression. J Consult Clin Psychol. 2014 Jun;82(3):418-28. doi: 10.1037/a0036033. Epub 2014 Mar 3.
PMID: 24588403DERIVEDTripp JC, Skidmore JR, Cui R, Tate SR. Impact of Physical Health on Treatment for Co-occurring Depression and Substance Dependence. J Dual Diagn. 2013;9(3):10.1080/15504263.2013.806111. doi: 10.1080/15504263.2013.806111.
PMID: 24223036DERIVEDWorley MJ, Tate SR, McQuaid JR, Granholm EL, Brown SA. 12-step affiliation and attendance following treatment for comorbid substance dependence and depression: a latent growth curve mediation model. Subst Abus. 2013;34(1):43-50. doi: 10.1080/08897077.2012.691451.
PMID: 23327503DERIVEDWorley MJ, Tate SR, Brown SA. Mediational relations between 12-Step attendance, depression and substance use in patients with comorbid substance dependence and major depression. Addiction. 2012 Nov;107(11):1974-83. doi: 10.1111/j.1360-0443.2012.03943.x. Epub 2012 Aug 10.
PMID: 22578037DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sandra Brown, PhD
VA San Diego Healthcare System, San Diego
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Intervention Model
- PARALLEL
- Sponsor Type
- FED
Study Record Dates
First Submitted
April 14, 2005
First Posted
April 15, 2005
Study Start
October 1, 2004
Last Updated
March 6, 2009
Record last verified: 2009-03