NCT00104585

Brief Summary

The purpose of this study is to investigate genetic and environmental risk factors that increase susceptibility to the development of early-onset Parkinson's disease (developed at or before age 50).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
750

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2004

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2004

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

March 1, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 2, 2005

Completed
9.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2014

Completed
Last Updated

July 24, 2024

Status Verified

July 1, 2024

Enrollment Period

10.3 years

First QC Date

March 1, 2005

Last Update Submit

July 23, 2024

Conditions

Parkinson's Disease

Keywords

Parkinson's diseasePDgeneenvironmentearly-onset Parkinson's disease

Study Arms (1)

Young onset Parkinson's disease

People with young onset Parkinson's disease and their family members

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Young onset Parkinson's disease patients

You may qualify if:

  • Any person with Parkinson's disease in the United States
  • Symptoms occurred before the age of 50
  • Diagnosed by a neurologist.

You may not qualify if:

  • Children who are \<18 years of age
  • Any probands who are cognitively impaired

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Columbia University

New York, New York, 10032, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

whole blood

MeSH Terms

Conditions

Parkinson DiseaseParkinsonian Disorders

Condition Hierarchy (Ancestors)

Basal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Karen Marder, M.D., M.PH.

    Columbia University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 1, 2005

First Posted

March 2, 2005

Study Start

July 1, 2004

Primary Completion

November 1, 2014

Study Completion

November 1, 2014

Last Updated

July 24, 2024

Record last verified: 2024-07

Locations

US(1)