A Research Study of How Teens With and Without an Anxiety Disorder Make Decisions

NCT00104195 | Completed

• 1 other identifier: H11610
• Study Type: observational
• Target: 127
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this trial is to study how teens with and without an anxiety disorder make decisions. This is a brain imaging study using functional magnetic resonance imaging (fMRI) in adolescents between the ages of 13 and 17.

Conditions

Anxiety Disorders; Separation Anxiety Disorder; Phobic Disorders

Keywords

Anxiety; Adolescence; Generalized Anxiety Disorder

Outcome Measures

Primary Outcomes (1)

• Intolerance of Uncertainty

  at time of assessment/enrollment

Eligibility Criteria

• Age: 13 Years - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Anxious and healthy adolescents

You may qualify if:

• Must meet diagnostic criteria for Generalized Anxiety Disorder, Separation Anxiety Disorder or Social Phobia, OR must be free of medical, psychiatric, neurologic conditions and learning disorders (healthy controls)
• Sufficient intelligence to understand the study and provide truly informed consent; will be determined by educational history

You may not qualify if:

• Having any major medical conditions that may interfere with interpretation of results or be associated with risk in an MRI environment (history of metal implants, or contraindications to MRI scanning for research purposes, including pregnancy)
• Current evidence of Autism, Major Depression, Substance Abuse, Obsessive Compulsive Disorder, Post-traumatic Stress Disorder, Panic Disorder, Tic Disorders, significant suicidality, lifetime history of psychosis or mania.
• Estimated Full-Scale IQ below 80
• Inability or unwillingness to remain still during scanning
• Inability or unwillingness to provide assent
• Absence of signed consent by parent or legal guardian
• Current history of sexual or physical abuse in the family, or past sexual or physical abuse if there is ongoing Department of Social Services (DSS) involvement

Sponsors & Collaborators

• NYU Langone Health: lead

Study Sites (1)

New York University's Child Study Center

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

Anxiety Disorders; Anxiety, Separation; Phobic Disorders; Generalized Anxiety Disorder

Condition Hierarchy (Ancestors)

Mental Disorders; Neurodevelopmental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 23, 2005
• First Posted: February 24, 2005
• Study Start: February 1, 2004
• Primary Completion: April 1, 2014
• Study Completion: April 1, 2014
• Last Updated: April 16, 2014

Record last verified: 2014-04

Locations

US (1)