Collection of Specimens for Study of Inflammatory Bowel Disease

NCT00086554 | Completed

• 2 other identifiers: 04023104-I-0231
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

This study will collect tissue specimens to be used for research on inflammatory bowel disease. The tissues will be used to explore why people get inflammatory bowel disease and to try to develop new treatments based on the study results. Tissue from patients with IBD will be compared with that from patients who do not have the disease Patients who undergo bowel surgery for inflammatory bowel disease (IBD) or another bowel disorder may be eligible for this study. Patients with IBD must be at least 4 years of age; those with another disorder must be 18 years of age or older. Participants undergo bowel surgery for their disease. Some of the intestinal tissue removed during the surgery that is not needed for medical care, such as for pathological examination, is provided to researchers for study under this protocol. In addition, patients with IBD provide a blood sample for genetic testing. Several genetic variations, or mutations, may increase the risk of developing IBD; blood samples from patients may help identify these variations.

Conditions

Inflammatory Bowel Diseases

Keywords

Surgery; Intestinal Resection; Blood Sample

Eligibility Criteria

• Age: 4 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Presence of idiopathic inflammatory bowel disease as established by prior endoscopic, histologic, and/or radiographic findings.
• Ability to give consent or have legally authorized person give consent and agree to sample storage.

You may not qualify if:

• \. Less than 4 years old.
• Absence of idiopathic inflammatory bowel disease as established by tests that exclude these diagnoses.
• Ability to give consent and agree to sample storage.
• \. Less than 18 years of age.

Sponsors & Collaborators

• National Institute of Allergy and Infectious Diseases (NIAID): lead

Study Sites (1)

National Institutes of Health Clinical Center, 9000 Rockville Pike

Bethesda, Maryland, 20892, United States

Location

MeSH Terms

Conditions

Inflammatory Bowel Diseases

Condition Hierarchy (Ancestors)

Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases

Study Design

• Study Type: observational
• Sponsor Type: NIH

Study Record Dates

• First Submitted: July 2, 2004
• First Posted: July 5, 2004
• Study Start: July 1, 2004
• Study Completion: January 8, 2010
• Last Updated: July 2, 2017

Record last verified: 2010-01-08

Locations

US (1)