NCT00078052

Brief Summary

To investigate genetic markers of coronary heart disease in type 2 diabetes.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2003

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2003

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 17, 2004

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 19, 2004

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2008

Completed
Last Updated

March 20, 2013

Status Verified

March 1, 2013

Enrollment Period

4.9 years

First QC Date

February 17, 2004

Last Update Submit

March 18, 2013

Conditions

Cardiovascular DiseasesCoronary DiseaseDiabetes Mellitus, Non-insulin DependentDiabetes MellitusHeart Diseases

Outcome Measures

Primary Outcomes (1)

  • cardiovascular disease

    1990-2006

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Nurses' Health Study and Health Professionals' Follow-up Study

no history of CVD or cancer at baseline

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (1)

  • Ma X, Bacci S, Mlynarski W, Gottardo L, Soccio T, Menzaghi C, Iori E, Lager RA, Shroff AR, Gervino EV, Nesto RW, Johnstone MT, Abumrad NA, Avogaro A, Trischitta V, Doria A. A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet. 2004 Oct 1;13(19):2197-205. doi: 10.1093/hmg/ddh233. Epub 2004 Jul 28.

    PMID: 15282206BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

Plasma and buffy coat

MeSH Terms

Conditions

Cardiovascular DiseasesCoronary DiseaseDiabetes Mellitus, Type 2Diabetes MellitusHeart Diseases

Condition Hierarchy (Ancestors)

Myocardial IschemiaVascular DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Frank Hu

    Harvard School of Public Health (HSPH)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 17, 2004

First Posted

February 19, 2004

Study Start

September 1, 2003

Primary Completion

August 1, 2008

Study Completion

August 1, 2008

Last Updated

March 20, 2013

Record last verified: 2013-03