Preventing Unplanned Pregnancies in HIV Infected Zambian Couples

NCT00067522 | Unknown

• 2 other identifiers: HD401251R01HD040125-01A1
• Study Type: interventional
• Target: 5,000
• Locations: 1 country
• Sites: 1

Brief Summary

Prevention of unplanned pregnancies among HIV infected couples decreases the rate of maternal-child virus transmission and the number of children orphaned when parents die of AIDS. This study will evaluate two programs for reducing the number of unplanned pregnancies among HIV infected couples in Zambia.

Conditions

Pregnancy; HIV Infections

Keywords

Family Planning; Sexually Transmitted Diseases; HIV; Africa; Zambia; AIDS; Contraception; HIV Prevention

Outcome Measures

Primary Outcomes (1)

• pregnancy

Interventions

User-independent contraception program BEHAVIORAL

Future Planning Perspectives program BEHAVIORAL

Eligibility Criteria

• Age: 16 Years - 38 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Couples with one or both partners with HIV infection

You may not qualify if:

• Pregnant or \< 1 month post-partum (couples will be invited to return when the infant is \> 1 month old)
• Peri- or post-menopausal
• Surgical sterilization or hysterectomy
• Documented infertility

Sponsors & Collaborators

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): lead

Study Sites (1)

Zambia Emory HIV Research Project

Lusaka, Zambia

Location

Related Publications (3)

• Wall KM, Haddad L, Vwalika B, Htee Khu N, Brill I, Kilembe W, Stephenson R, Chomba E, Vwalika C, Tichacek A, Allen S. Unintended pregnancy among HIV positive couples receiving integrated HIV counseling, testing, and family planning services in Zambia. PLoS One. 2013 Sep 30;8(9):e75353. doi: 10.1371/journal.pone.0075353. eCollection 2013.

  PMID: 24098692 DERIVED

• Haddad L, Wall KM, Vwalika B, Khu NH, Brill I, Kilembe W, Stephenson R, Chomba E, Vwalika C, Tichacek A, Allen S. Contraceptive discontinuation and switching among couples receiving integrated HIV and family planning services in Lusaka, Zambia. AIDS. 2013 Oct;27 Suppl 1(0 1):S93-103. doi: 10.1097/QAD.0000000000000039.

  PMID: 24088689 DERIVED

• Wall KM, Vwalika B, Haddad L, Khu NH, Vwalika C, Kilembe W, Chomba E, Stephenson R, Kleinbaum D, Nizam A, Brill I, Tichacek A, Allen S. Impact of long-term contraceptive promotion on incident pregnancy: a randomized controlled trial among HIV-positive couples in Lusaka, Zambia. J Acquir Immune Defic Syndr. 2013 May 1;63(1):86-95. doi: 10.1097/QAI.0b013e31827ee19c.

  PMID: 23202814 DERIVED

MeSH Terms

Conditions

HIV Infections; Sexually Transmitted Diseases; Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Slow Virus Diseases

Study Officials

• Susan Allen, MD, MPH

  Emory University, Rollins School of Public Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Purpose: PREVENTION
• Intervention Model: FACTORIAL
• Sponsor Type: NIH

Study Record Dates

• First Submitted: August 21, 2003
• First Posted: August 25, 2003
• Study Start: January 1, 2002
• Last Updated: June 29, 2007

Record last verified: 2005-09

Locations

ZA (1)