The Framingham Study: Examining DNA Markers and Links to Diseases
A Genome-Wide Scan for Quantitative Trait Loci of Hematocrit - A Framingham Study
2 other identifiers
observational
330
1 country
1
Brief Summary
Since 1948, residents of Framingham, Massachusetts, have participated in a program that collects blood samples and clinical data to provide a rare and valuable database for scientific research. The purpose of this study is to support this national resource by aiding in its research capacity. Specifically, researchers in this study will (1) investigate heart, lung, and blood diseases; stroke; memory loss; joint disease; bone loss; deafness; cancer; blood vessel diseases and other health conditions, and (2) examine DNA and its relationship to risk of developing these disease and health conditions. Approximately 330 families have participated in the Framingham Study. Participants will be required to undergo a four-hour exam and to take that exam every two years thereafter. During the exam, the Framingham investigators will (1) interview participants about medical status, health issues, and lifestyles; (2) perform a regular physical exam; (3) obtain blood and urine samples and administer a glucose-tolerance test; (4) supervise a brisk six-minute treadmill walk; (5) administer an ultrasound procedure; and (6) review and obtain copies of medical and hospital records. Participants will also be asked to complete a questionnaire at home regarding dietary and health habits.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2003
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 12, 2003
CompletedFirst Submitted
Initial submission to the registry
June 13, 2003
CompletedFirst Posted
Study publicly available on registry
June 16, 2003
CompletedStudy Completion
Last participant's last visit for all outcomes
June 16, 2011
CompletedJuly 2, 2017
June 16, 2011
June 13, 2003
June 30, 2017
Conditions
Keywords
Eligibility Criteria
You may not qualify if:
- The study population will include the members of the 330 Framingham Study families with genome scan.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, 20892, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Sponsor Type
- NIH
Study Record Dates
First Submitted
June 13, 2003
First Posted
June 16, 2003
Study Start
June 12, 2003
Study Completion
June 16, 2011
Last Updated
July 2, 2017
Record last verified: 2011-06-16