Retraining Walking After Spinal Cord Injury

NCT00059553 | Unknown Phase 2

• 1 other identifier: K01HD001348
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

Incomplete spinal cord injury often results in difficulty walking. Training on a treadmill with body weight support may improve walking ability after spinal cord injury. The purpose of this study is to examine the effect of treadmill speed on spinal cord function and walking performance.

Conditions

Spinal Cord Injuries; Quadriplegia; Paraplegia; Central Cord Syndrome; Brown-Sequard Syndrome

Keywords

spinal cord injury; walking; training; treadmill; incomplete spinal cord injury

Interventions

Locomotor treadmill training with body weight support BEHAVIORAL

Eligibility Criteria

• Age: 6 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• First time spinal cord injury (SCI) from trauma, vascular, or orthopedic pathology at cervical or thoracic levels
• Category C or D SCI as defined by the American Spinal Injury Association (ASIA) Impairment Scale
• to 3 years post-SCI
• Ability to walk independently a minimum of 40 feet with or without an assistive device
• Currently spending a minimum of 30 minutes per day walking
• No change in anti-spasticity medication during the study
• Medically stable
• Participant's personal physician must verify the participant's medical status

You may not qualify if:

• Bladder infection, decubiti, osteoporosis, cardiopulmonary disease, pain, or other significant medical complications that would prohibit or interfere with training and testing of walking function or alter compliance with a training protocol
• Currently participating in a rehabilitation program or another research protocol that could interfere or influence the outcome measures of the current study
• Congenital SCI (e.g., Chiari malformation, myelomeningocele, intraspinal neoplasm, Frederich's ataxia)
• Other degenerative spinal disorders (e.g., spinocerebellar degeneration, syringomyelia) that may complicate the treatment or evaluation procedures

Sponsors & Collaborators

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): lead
• US Department of Veterans Affairs: collaborator

Study Sites (1)

University of Florida

Gainesville, Florida, 32610, United States

Location

Related Publications (2)

• Behrman AL, Harkema SJ. Locomotor training after human spinal cord injury: a series of case studies. Phys Ther. 2000 Jul;80(7):688-700.

  PMID: 10869131 BACKGROUND

• Barbeau H, Norman K, Fung J, Visintin M, Ladouceur M. Does neurorehabilitation play a role in the recovery of walking in neurological populations? Ann N Y Acad Sci. 1998 Nov 16;860:377-92. doi: 10.1111/j.1749-6632.1998.tb09063.x.

  PMID: 9928326 BACKGROUND

Related Links

• Departmental Website for Principal Investigator
• Website for Principal Investigator in Rehabilitation Science PhD Program

MeSH Terms

Conditions

Spinal Cord Injuries; Quadriplegia; Paraplegia; Central Cord Syndrome; Brown-Sequard Syndrome

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Andrea L Behrman, PhD

  University of Florida

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: NIH

Study Record Dates

• First Submitted: April 28, 2003
• First Posted: April 29, 2003
• Study Start: May 1, 2000
• Study Completion: January 1, 2005
• Last Updated: June 18, 2009

Record last verified: 2005-08

Locations

US (1)