NCT00148239

Brief Summary

The overall objective of this project is to test the efficacy of an innovative multi-component intervention aimed at reducing the risk for adverse health outcomes among caregivers of older survivors with spinal cord injury or disability, and to improve the well being of the spinal cord-injured survivor. In a three-group, randomized, controlled design providing access to information, resources, and support, we predict that the dual target approach will have a greater positive impact on both the caregiver and survivor than the caregiver-only approach, and that both active treatments will be superior with respect to caregiver outcomes than an information-only control condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
380

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Sep 2002

Longer than P75 for phase_2

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2002

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

September 2, 2005

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 7, 2005

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2007

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
Last Updated

December 2, 2015

Status Verified

November 1, 2015

Enrollment Period

4.8 years

First QC Date

September 2, 2005

Last Update Submit

November 30, 2015

Conditions

Keywords

SCICaregivingAgingDisabilityParalysis

Outcome Measures

Primary Outcomes (4)

  • Depressive symptoms caregivers and SCI

    6 and 12 months post-randomization

  • Caregiver Burden

    6 and 12 months

  • Social support caregiver and SCI

    6 and 12 months

  • Health symptoms caregiver and SCI

    6 and 12 months

Study Arms (3)

Caregiver Only

EXPERIMENTAL

A multi-component psycho-educational intervention designed to reduce the negative emotional and behavioral responses of the caregiver and reduce the risk of mental and physical health problems.

Behavioral: Caregiver Only Intervention

Dual Treatment

EXPERIMENTAL

Complements the caregiver only intervention by targetting both caregiver and SCI person with multi-component psycho-educational intervention

Behavioral: Dual Treatment

Control

ACTIVE COMPARATOR

Participants are provided with written materials at beginning of study; nothing thereafter

Behavioral: Control

Interventions

A multi-component psycho-educational intervention designed to reduce the negative emotional and behavioral responses of the caregiver and reduce the risk of mental and physical health problems.

Caregiver Only
Dual TreatmentBEHAVIORAL

Complements the caregiver only intervention by targetting both caregiver and SCI person with multi-component psycho-educational intervention

Dual Treatment
ControlBEHAVIORAL

Participants given written educational materials at beginning of study; no treatment beyond this

Control

Eligibility Criteria

Age30 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • have adult-onset disability resulting from spinal cord injury, trauma, or disease,
  • be survivors with complete or incomplete injury as defined by the American Spinal Injury Association (ASIA) impairment scale
  • require and use some type of assistance for getting around (e.g., wheelchair, cane, etc.) be 30 years old or older be living at home for a minimum of 1 year post-injury (to avoid the acute trauma phase) speak English.
  • Is a family member/partner (e.g. spouse, child, or fictive kin)
  • is 18 years of age or older
  • is or is not living with the care recipient
  • speaks English
  • has a telephone at home
  • plans to live in the area for at least 6 months.
  • self-identifies as white, African American or Hispanic.

You may not qualify if:

  • has a terminal illness with life expectancy of less than 6 months
  • is in active treatment for cancer (except for tamoxifen and lupron)
  • is blind or deaf
  • if the survivor is cognitively impaired due to brain injury or dementia and/or has no use of their hands and severe limitations in speech production

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Miami

Miami, Florida, 33136, United States

Location

University of Pittsburgh (UCSUR)

Pittsburgh, Pennsylvania, 15260, United States

Location

Related Publications (1)

  • Schulz R, Czaja SJ, Lustig A, Zdaniuk B, Martire LM, Perdomo D. Improving the quality of life of caregivers of persons with spinal cord injury: a randomized controlled trial. Rehabil Psychol. 2009 Feb;54(1):1-15. doi: 10.1037/a0014932.

MeSH Terms

Conditions

Spinal Cord InjuriesParalysis

Condition Hierarchy (Ancestors)

Spinal Cord DiseasesCentral Nervous System DiseasesNervous System DiseasesTrauma, Nervous SystemWounds and InjuriesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Richard Schulz, PhD

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. of Psychiatry

Study Record Dates

First Submitted

September 2, 2005

First Posted

September 7, 2005

Study Start

September 1, 2002

Primary Completion

July 1, 2007

Study Completion

July 1, 2008

Last Updated

December 2, 2015

Record last verified: 2015-11

Locations