NCT00047996|Enrolling By Invitation
Blood Collection for Research Related to Certain Diseases Involving Blood Vessels
Human Specimen Collection to Support Basic and Clinical Research
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Human Specimen Collection to Support Basic and Clinical Research
Sponsor study identifier
Secondary identifiers
observational
2,000
1 country
2
Study Start
November 4, 2002
Actual (reported)Primary Completion
Not reported
Date not reportedStudy Completion
Not reported
Date not reportedThe collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
Not reported
Date not reportedClick on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 23, 2002
Actual (reported)November 4, 2002
Actual (reported)July 11, 2006
Actual (reported)evaluating the role of nitric oxide, inflammatory mediators, and endothelial function in inflammatory diseases of the vasculature such as sickle cell disease, coronary artery disease, pulmonary vascular or advanced lung disease, malaria, and sep...
Clinical Center Patients, Healthy Volunteers
Normal subjects, Male/Female
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
INOVA Fairfax Hosptial
Fairfax, Virginia, 22042, United States
Tumburu L, Ghosh-Choudhary S, Seifuddin FT, Barbu EA, Yang S, Ahmad MM, Wilkins LHW, Tunc I, Sivakumar I, Nichols JS, Dagur PK, Yang S, Almeida LEF, Quezado ZMN, Combs CA, Lindberg E, Bleck CKE, Zhu J, Shet AS, Chung JH, Pirooznia M, Thein SL. Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease. Blood. 2021 Jun 3;137(22):3116-3126. doi: 10.1182/blood.2020009063.
Swee Lay Thein, M.D.
National Heart, Lung, and Blood Institute (NHLBI)
First Submitted
July 11, 2006
First Posted
October 23, 2002
Study Start
November 4, 2002
Actual (reported)Last Updated
October 26, 2026
Record last verified: 2026-10-19
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Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved:
Niacin to Improve Blood Flow in People With Sickle Cell Disease
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