Iressa Expanded Access Program (EAP)
An Expanded Access Clinical Program With ZD1839 (IRESSA®) for Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
1 other identifier
interventional
N/A
1 country
626
Brief Summary
A program for patients with non small cell lung cancer who may benefit from Iressa, but cannot enter another clinical trial due to them not being eligible, or for whom no trials are available.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Aug 2000
Typical duration for phase_3
626 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2000
CompletedFirst Submitted
Initial submission to the registry
May 2, 2002
CompletedFirst Posted
Study publicly available on registry
May 3, 2002
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2003
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2003
CompletedJanuary 4, 2013
January 1, 2013
3.2 years
May 2, 2002
January 3, 2013
Conditions
Keywords
Interventions
Eligibility Criteria
You may qualify if:
- previous documented histologically or cytologically confirmed non-small cell lung cancer;
- locally advanced and/or metastatic non-operable non-small cell lung cancer (stage III or IV)patients who have received at least one course of standard systemic chemotherapy or radiation therapy or are ineligible for chemotherapy or radiotherapy or are ineligible or not a candidate for enrollment on another ZD1839 trial or who, in the Investigator's opinion, are not medically suitable for chemotherapy.
- age 18 years or older;
- written informed consent to participate in the trial.
You may not qualify if:
- Any of the following will exclude a patient from entering the trial:
- receiving concurrent radiotherapy, chemotherapy, or other systemic anti-cancer medication or any other investigational agent. \* Non-cytotoxic or hormonal therapies for the adjuvant treatment of cancer or for previously treated cancers may be allowed per AstraZeneca permission;
- patients eligible for or previously enrolled on a ZD1839 blinded clinical trial protocol. Patients eligible for or previously enrolled on an open-label or unblinded ZD1839 clinical trial may be considered for acceptance into the Expanded Access Program with AstraZeneca permission;
- having other active malignancies;
- incomplete healing from previous oncologic or other major surgery;
- evidence of any other significant clinical disorder or laboratory finding that makes it undesirable for the patient to participate in the trial;
- pregnancy or breast feeding (women of child-bearing potential).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- AstraZenecalead
Study Sites (626)
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Alabaster, Alabama, United States
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Anniston, Alabama, United States
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Birmingham, Alabama, United States
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Gadsen, Alabama, United States
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Huntsville, Alabama, United States
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Montgomery, Alabama, United States
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Anchorage, Alaska, United States
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Fairbanks, Alaska, United States
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Mesa, Arizona, United States
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Phoenix, Arizona, United States
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Scottsdale, Arizona, United States
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Sedona, Arizona, United States
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Tucson, Arizona, United States
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Yuma, Arizona, United States
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Bentonville, Arkansas, United States
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Camden, Arkansas, United States
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Fort Smith, Arkansas, United States
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Little Rock, Arkansas, United States
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Anaheim, California, United States
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Arcadia, California, United States
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Bakersfield, California, United States
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Baldwin Park, California, United States
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Bellflower, California, United States
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Berkeley, California, United States
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Burbank, California, United States
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Campbell, California, United States
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Chico, California, United States
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Chino, California, United States
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Chule Vista, California, United States
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Concord, California, United States
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Duarte, California, United States
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Eureka, California, United States
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Fairfield, California, United States
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Fontana, California, United States
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Fountain Valley, California, United States
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Fresno, California, United States
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Fullerton, California, United States
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Gilroy, California, United States
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Grass Valley, California, United States
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Greenbrae, California, United States
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La Jolla, California, United States
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Lakewood, California, United States
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LaVerne, California, United States
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Loma Linda, California, United States
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Long Beach, California, United States
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Los Alamitos, California, United States
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Los Angeles, California, United States
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Los Gatos, California, United States
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Marina Del Ray, California, United States
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Mission Viejo, California, United States
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Montebello, California, United States
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Monterey, California, United States
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Newport Beach, California, United States
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Oakland, California, United States
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Oceanside, California, United States
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Orange, California, United States
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Oxnard, California, United States
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Palm Springs, California, United States
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Palo Alto, California, United States
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Panorama City, California, United States
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Petaluma, California, United States
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Pleasanton, California, United States
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Rancho Mirage, California, United States
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Redding, California, United States
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Redondo Beach, California, United States
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Redwood City, California, United States
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Riverside, California, United States
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Royal Grande, California, United States
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Sacramento, California, United States
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Salinas, California, United States
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San Diego, California, United States
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San Francisco, California, United States
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San Jose, California, United States
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San Luis Obispo, California, United States
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San Mateo, California, United States
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Santa Barbara, California, United States
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Santa Clara, California, United States
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Santa Cruz, California, United States
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Santa Maria, California, United States
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Santa Monica, California, United States
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Simi Valley, California, United States
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Soquel, California, United States
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Stockton, California, United States
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Sunnyvale, California, United States
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Sylmar, California, United States
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Tarzana, California, United States
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Thousand Oaks, California, United States
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Twentynine Palm, California, United States
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Upland, California, United States
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Vallejo, California, United States
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Van Nuys, California, United States
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Walnut Creek, California, United States
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Westlake Village, California, United States
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Woodland Hills, California, United States
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Boulder, Colorado, United States
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Denver, Colorado, United States
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Fort Collins, Colorado, United States
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Longmont, Colorado, United States
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Pueblo, Colorado, United States
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Danbury, Connecticut, United States
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Fairfield, Connecticut, United States
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Greenwich, Connecticut, United States
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Handen, Connecticut, United States
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Hartford, Connecticut, United States
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Manchester, Connecticut, United States
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Middletown, Connecticut, United States
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Milford, Connecticut, United States
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New London, Connecticut, United States
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New Milford, Connecticut, United States
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Norwalk, Connecticut, United States
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Norwich, Connecticut, United States
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Stamford, Connecticut, United States
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Torrington, Connecticut, United States
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Trumbull, Connecticut, United States
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Waterbury, Connecticut, United States
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Lewes, Delaware, United States
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Newark, Delaware, United States
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Washington D.C., District of Columbia, United States
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Boca Raton, Florida, United States
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Boynton Beach, Florida, United States
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Bradenton, Florida, United States
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Clearwater, Florida, United States
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Daytona Beach, Florida, United States
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Fort Myers, Florida, United States
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Gainesville, Florida, United States
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Jacksonville, Florida, United States
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Jupiter, Florida, United States
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Key West, Florida, United States
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Lake Worth, Florida, United States
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Lakeland, Florida, United States
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Leesburg, Florida, United States
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Melbourne, Florida, United States
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Miami, Florida, United States
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Miami Shores, Florida, United States
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Naples, Florida, United States
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New Port Richey, Florida, United States
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Ocala, Florida, United States
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Ocoee, Florida, United States
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Orange Park, Florida, United States
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Orlando, Florida, United States
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Ormand Beach, Florida, United States
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Palm Harbor, Florida, United States
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Panama City, Florida, United States
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Pensacola, Florida, United States
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Plantation, Florida, United States
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Port Charlotte, Florida, United States
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Port Saint Lucie, Florida, United States
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Saint Augustine, Florida, United States
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Sanford, Florida, United States
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Sarasota, Florida, United States
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St. Petersburg, Florida, United States
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Stuart, Florida, United States
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Tampa, Florida, United States
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Tavares, Florida, United States
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Vero Beach, Florida, United States
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West Palm Beach, Florida, United States
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Albany, Georgia, United States
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Athens, Georgia, United States
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Atlanta, Georgia, United States
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Brunswick, Georgia, United States
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Canton, Georgia, United States
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Carrollton, Georgia, United States
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Fort Gordon, Georgia, United States
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Macon, Georgia, United States
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Marietta, Georgia, United States
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Roswell, Georgia, United States
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Savannah, Georgia, United States
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Thomasville, Georgia, United States
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Tucker, Georgia, United States
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Valdosta, Georgia, United States
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Waycross, Georgia, United States
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Honolulu, Hawaii, United States
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Tripler AMC, Hawaii, United States
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Wailuku, Hawaii, United States
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Boise, Idaho, United States
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Coeur d'Alene, Idaho, United States
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Idaho Falls, Idaho, United States
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Arlington Heights, Illinois, United States
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Aurora, Illinois, United States
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Belleville, Illinois, United States
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Berwyn, Illinois, United States
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Champaign, Illinois, United States
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Chicago, Illinois, United States
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Chicago Heights, Illinois, United States
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Danville, Illinois, United States
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Decatur, Illinois, United States
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Des Plaines, Illinois, United States
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Elk Grove Village, Illinois, United States
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Elmhurst, Illinois, United States
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Evanston, Illinois, United States
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Flossmore, Illinois, United States
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Galesburg, Illinois, United States
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Geneva, Illinois, United States
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Harvey, Illinois, United States
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Hinsdale, IL, Illinois, United States
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Joliet, Illinois, United States
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La Grange, Illinois, United States
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Libertyville, Illinois, United States
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Maywood, Illinois, United States
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Moline, Illinois, United States
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Naperville, Illinois, United States
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Oak Lawn, Illinois, United States
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Park Ridge, Illinois, United States
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Peoria, Illinois, United States
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River Forest, Illinois, United States
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Rockford, Illinois, United States
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Skokie, Illinois, United States
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Springfield, Illinois, United States
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Urbana, Illinois, United States
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Wheaton, Illinois, United States
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Zion, Illinois, United States
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Bloomington, Indiana, United States
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Evansville, Indiana, United States
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Fort Wayne, Indiana, United States
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Indianapolis, Indiana, United States
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Jasper, Indiana, United States
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Merrillville, Indiana, United States
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Michigan City, Indiana, United States
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Muncie, Indiana, United States
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Munster, Indiana, United States
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New Albany, Indiana, United States
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South Bend, Indiana, United States
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Terre Haute, Indiana, United States
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Ames, Iowa, United States
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Bettendorf, Iowa, United States
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Davenport, Iowa, United States
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Des Moines, Iowa, United States
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Iowa City, Iowa, United States
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Mason City, Iowa, United States
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Sioux City, Iowa, United States
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Waterloo, Iowa, United States
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Hays, Kansas, United States
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Hutchinson, Kansas, United States
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Kansas City, Kansas, United States
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Lawrence, Kansas, United States
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Lenexa, Kansas, United States
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Topeka, Kansas, United States
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Witchita, Kansas, United States
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Ashland, Kentucky, United States
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Danville, Kentucky, United States
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Hazard, Kentucky, United States
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Lexington, Kentucky, United States
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Louisville, Kentucky, United States
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Paducah, Kentucky, United States
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Pikeville, Kentucky, United States
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Trenton, Kentucky, United States
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Baton Rouge, Louisiana, United States
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Debque, Louisiana, United States
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Lafayette, Louisiana, United States
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Lake Charles, Louisiana, United States
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Metairie, Louisiana, United States
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New Orleans, Louisiana, United States
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Shreveport, Louisiana, United States
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Slidell, Louisiana, United States
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Thiodaux, Louisiana, United States
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Bangor, Maine, United States
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Scarborough, Maine, United States
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Waterville, Maine, United States
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York Village, Maine, United States
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Baltimore, Maryland, United States
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Bethesda, Maryland, United States
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Cumberland, Maryland, United States
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Olney, Maryland, United States
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Rockville, Maryland, United States
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Towson, Maryland, United States
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Waldorf, Maryland, United States
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Beverly, Massachusetts, United States
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Boston, Massachusetts, United States
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Brockton, Massachusetts, United States
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Burlington, Massachusetts, United States
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Chicopee, Massachusetts, United States
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Lowell, Massachusetts, United States
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Mansfield, Massachusetts, United States
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Medford, Massachusetts, United States
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Pittsfield, Massachusetts, United States
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Quincy, Massachusetts, United States
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South Weymouth, Massachusetts, United States
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Springfield, Massachusetts, United States
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Stoneham, Massachusetts, United States
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Taunton, Massachusetts, United States
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Walpole, Massachusetts, United States
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Wareham, Massachusetts, United States
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Wellesley, Massachusetts, United States
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Woburn, Massachusetts, United States
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Worchester, Massachusetts, United States
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Battle Kreek, Michigan, United States
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Bay City, Michigan, United States
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Detroit, Michigan, United States
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Flint, Michigan, United States
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Free Soil, Michigan, United States
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Golfport, Michigan, United States
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Grand Rapids, Michigan, United States
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Grosse Point Woods, Michigan, United States
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Iron Mountain, Michigan, United States
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Jackson, Michigan, United States
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Kalamazoo, Michigan, United States
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Lansing, Michigan, United States
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Lapeer, Michigan, United States
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Marquette, Michigan, United States
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Midland, Michigan, United States
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Mount Clemens, Michigan, United States
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Muskegon, Michigan, United States
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Petoskey, Michigan, United States
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Poplar Buff, Michigan, United States
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Port Huron, Michigan, United States
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Roseville, Michigan, United States
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Royal Oak, Michigan, United States
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Saint Joseph, Michigan, United States
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Southfield, Michigan, United States
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Traverse City, Michigan, United States
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Ypsilanti, Michigan, United States
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Alexandria, Minnesota, United States
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Bemidji, Minnesota, United States
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Brainerd, Minnesota, United States
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Duluth, Minnesota, United States
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Maplewood, Minnesota, United States
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Minneapolis, Minnesota, United States
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Roseville, Minnesota, United States
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Saint Cloud, Minnesota, United States
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Saint Louis Park, Minnesota, United States
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Hattiesburg, Mississippi, United States
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Jackson, Mississippi, United States
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Pascagoula, Mississippi, United States
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Tupelo, Mississippi, United States
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Branson, Missouri, United States
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Chesterfield, Missouri, United States
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Columbia, Missouri, United States
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Creve Coeus, Missouri, United States
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Joplin, Missouri, United States
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Kansas City, Missouri, United States
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Poplar Bluff, Missouri, United States
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Saint Charles, Missouri, United States
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Springfield, Missouri, United States
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St Louis, Missouri, United States
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Billings, Montana, United States
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Great Falls, Montana, United States
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Helena, Montana, United States
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Grand Island, Nebraska, United States
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Lincoln, Nebraska, United States
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Omaha, Nebraska, United States
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Las Vegas, Nevada, United States
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Reno, Nevada, United States
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Hooksett, New Hampshire, United States
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Lebanon, New Hampshire, United States
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Nashua, New Hampshire, United States
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Belleville, New Jersey, United States
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Denville, New Jersey, United States
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Elizabeth, New Jersey, United States
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Englewood, New Jersey, United States
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Flemington, New Jersey, United States
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Galloway, New Jersey, United States
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Hackensack, New Jersey, United States
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Little Silver, New Jersey, United States
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Livingston, New Jersey, United States
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Long Branch, New Jersey, United States
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Mahwah, New Jersey, United States
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Manasquan, New Jersey, United States
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Montclair, New Jersey, United States
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Morristown, New Jersey, United States
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Mount Holly, New Jersey, United States
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New Brunswick, New Jersey, United States
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Newark, New Jersey, United States
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Old Bridge, New Jersey, United States
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Paramus, New Jersey, United States
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Phillipsburg, New Jersey, United States
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Plainfield, New Jersey, United States
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Pompton Plains, New Jersey, United States
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Princeton, New Jersey, United States
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Red Bank, New Jersey, United States
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Somerset, New Jersey, United States
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Summit, New Jersey, United States
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Teaneck, New Jersey, United States
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Union, New Jersey, United States
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Voorhees Township, New Jersey, United States
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Westwood, New Jersey, United States
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Albuquerque, New Mexico, United States
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Farmington, New Mexico, United States
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Las Cruces, New Mexico, United States
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Roswell, New Mexico, United States
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Santa Fe, New Mexico, United States
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Albany, New York, United States
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Bay Shore, New York, United States
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Bayside, New York, United States
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Bronxville, New York, United States
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Brooklyn, New York, United States
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Buffalo, New York, United States
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Cooperstown, New York, United States
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East Setauket, New York, United States
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East Syracuse, New York, United States
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Flushing, New York, United States
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Fresh Meadows, New York, United States
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Geneseo, New York, United States
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Glen Cove, New York, United States
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Glens Falls, New York, United States
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Goshen, New York, United States
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Great Neck, New York, United States
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Harris, New York, United States
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Huntington, New York, United States
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Huntington Station, New York, United States
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Johnson City, New York, United States
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Lake Success, New York, United States
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Malone, New York, United States
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Merrick, New York, United States
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Mineola, New York, United States
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New Hyde Park, New York, United States
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New Rochelle, New York, United States
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New York, New York, United States
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Northport, New York, United States
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Nyack, New York, United States
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Pomona, New York, United States
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Port Washington, New York, United States
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Riverhead, New York, United States
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Rochester, New York, United States
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Rockville Centre, New York, United States
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Schenectady, New York, United States
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Staten Island, New York, United States
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Suffern, New York, United States
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Syosset, New York, United States
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The Bronx, New York, United States
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Utica, New York, United States
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Valhalla, New York, United States
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Valley Stream, New York, United States
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West Islip, New York, United States
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White Plains, New York, United States
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Wiliamsville, New York, United States
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Williamsville, New York, United States
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Woodbury, New York, United States
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Asheville, North Carolina, United States
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Boone, North Carolina, United States
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Burlington, North Carolina, United States
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Charlotte, North Carolina, United States
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Concord, North Carolina, United States
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Durham, North Carolina, United States
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Elizabeth, North Carolina, United States
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Fayetteville, North Carolina, United States
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Forest City, North Carolina, United States
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Goldsboro, North Carolina, United States
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Greensboro, North Carolina, United States
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Greenville, North Carolina, United States
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Hickory, North Carolina, United States
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Kinston, North Carolina, United States
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Raleigh, North Carolina, United States
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Salisbury, North Carolina, United States
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Valdese, North Carolina, United States
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Wilmington, North Carolina, United States
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Winston-Salem, North Carolina, United States
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Bismarck, North Dakota, United States
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Fargo, North Dakota, United States
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Grand Forks, North Dakota, United States
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Akron, Ohio, United States
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Barberton, Ohio, United States
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Bryan, Ohio, United States
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Canton, Ohio, United States
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Cincinnati, Ohio, United States
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Cleveland, Ohio, United States
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Columbus, Ohio, United States
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Dayton, Ohio, United States
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Fairfield, Ohio, United States
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Finley, Ohio, United States
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Independence, Ohio, United States
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Kettering, Ohio, United States
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Mansfield, Ohio, United States
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Mentor, Ohio, United States
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Middleburg Heights, Ohio, United States
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Middletown, Ohio, United States
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Sandusky, Ohio, United States
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Toledo, Ohio, United States
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Troy, Ohio, United States
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Warrensville Heights, Ohio, United States
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Wooster, Ohio, United States
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Youngstown, Ohio, United States
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Zanesville, Ohio, United States
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Enid, Oklahoma, United States
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Lawton, Oklahoma, United States
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Oklahoma City, Oklahoma, United States
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Ponca City, Oklahoma, United States
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Stillwater, Oklahoma, United States
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Tulsa, Oklahoma, United States
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Bend, Oregon, United States
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Coos Bay, Oregon, United States
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Corvallis, Oregon, United States
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Eugene, Oregon, United States
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Klamath, Oregon, United States
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Medford, Oregon, United States
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Portland, Oregon, United States
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Salem, Oregon, United States
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Tualatin, Oregon, United States
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Allentown, Pennsylvania, United States
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Bethlehem, Pennsylvania, United States
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Bryn Mawr, Pennsylvania, United States
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Butler, Pennsylvania, United States
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Cellarsville, Pennsylvania, United States
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Danville, Pennsylvania, United States
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Drexel Hill, Pennsylvania, United States
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Dunmore, Pennsylvania, United States
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East Stroudsburg, Pennsylvania, United States
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Easton, Pennsylvania, United States
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Ephrata, Pennsylvania, United States
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Erie, Pennsylvania, United States
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Franklin, Pennsylvania, United States
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Greensburg, Pennsylvania, United States
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Harrisburg, Pennsylvania, United States
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Hazleton, Pennsylvania, United States
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Kingston, Pennsylvania, United States
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Kittanning, Pennsylvania, United States
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Lancaster, Pennsylvania, United States
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Langhorne, Pennsylvania, United States
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Langhorn, Pennsylvania, United States
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Lemoyne, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Phoenixville, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Pottstown, Pennsylvania, United States
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Pottsville, Pennsylvania, United States
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Saint Marys, Pennsylvania, United States
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Sayre, Pennsylvania, United States
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Scranton, Pennsylvania, United States
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State College, Pennsylvania, United States
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West Reading, Pennsylvania, United States
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York, Pennsylvania, United States
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Pawtucket, Rhode Island, United States
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Providence, Rhode Island, United States
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Warwick, Rhode Island, United States
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Westerly, Rhode Island, United States
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Charleston, South Carolina, United States
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Columbia, South Carolina, United States
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Florence, South Carolina, United States
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Greenville, South Carolina, United States
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Mt. Pleasant, South Carolina, United States
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Myrtle Beach, South Carolina, United States
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Spartenburg, South Carolina, United States
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Aberdeen, South Dakota, United States
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Rapid City, South Dakota, United States
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Sioux Falls, South Dakota, United States
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Chattanooga, Tennessee, United States
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Collierville, Tennessee, United States
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Jackson, Tennessee, United States
Research Site
Johnson City, Tennessee, United States
Research Site
Knoxville, Tennessee, United States
Research Site
Memphis, Tennessee, United States
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Nashville, Tennessee, United States
Research Site
Abilene, Texas, United States
Research Site
Amarillo, Texas, United States
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Arlington, Texas, United States
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Austin, Texas, United States
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Baytown, Texas, United States
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Beaumont, Texas, United States
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Bryan, Texas, United States
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Corpus Christi, Texas, United States
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Dallas, Texas, United States
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El Paso, Texas, United States
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Fort Worth, Texas, United States
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Fredricksburg, Texas, United States
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Garland, Texas, United States
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Houston, Texas, United States
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Irving, Texas, United States
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Lewisville, Texas, United States
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Lubbock, Texas, United States
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McAllen, Texas, United States
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Mesquite, Texas, United States
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Midland, Texas, United States
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New Braunfels, Texas, United States
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Paris, Texas, United States
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Pasadena, Texas, United States
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Plano, Texas, United States
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Richmond, Texas, United States
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San Antonio, Texas, United States
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San Marcos, Texas, United States
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Sherman, Texas, United States
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Temple, Texas, United States
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Tyler, Texas, United States
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Victoria, Texas, United States
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Waco, Texas, United States
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Walla Walla, Texas, United States
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Webster, Texas, United States
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Ivins, Utah, United States
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Ogden, Utah, United States
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Salt Lake City, Utah, United States
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Bennington, Vermont, United States
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Rutland, Vermont, United States
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Abington, Virginia, United States
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Charlottesville, Virginia, United States
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Chesapeake, Virginia, United States
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Danville, Virginia, United States
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Fairfax, Virginia, United States
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Fredericksburg, Virginia, United States
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Hampton, Virginia, United States
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Lynchburg, Virginia, United States
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Newport News, Virginia, United States
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Norfolk, Virginia, United States
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Portsmouth, Virginia, United States
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Richmond, Virginia, United States
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Roanoke, Virginia, United States
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Williamsburg, Virginia, United States
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Woodridge, Virginia, United States
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Auburn, Washington, United States
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Bremerton, Washington, United States
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Kennewick, Washington, United States
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Kirkland, Washington, United States
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Mount Vernon, Washington, United States
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Olympia, Washington, United States
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Renton, Washington, United States
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Seattle, Washington, United States
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Spokane, Washington, United States
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Tacoma, Washington, United States
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Vancouver, Washington, United States
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Clarksburg, West Virginia, United States
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Huntington, West Virginia, United States
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Morgantown, West Virginia, United States
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Princeton, West Virginia, United States
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Wheeling, West Virginia, United States
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Appleton, Wisconsin, United States
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Eau Claire, Wisconsin, United States
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Green Bay, Wisconsin, United States
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Janesville, Wisconsin, United States
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La Crosse, Wisconsin, United States
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Madison, Wisconsin, United States
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Manitowoc, Wisconsin, United States
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Marshfield, Wisconsin, United States
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Milwaukee, Wisconsin, United States
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Racine, Wisconsin, United States
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Rhinelander, Wisconsin, United States
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Sheboygan, Wisconsin, United States
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Waukesha, Wisconsin, United States
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Wausau, Wisconsin, United States
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Cheyenne, Wyoming, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Iressa Medical Science Director, MD
AstraZeneca
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- INDUSTRY
- Expanded Access
- Yes
Study Record Dates
First Submitted
May 2, 2002
First Posted
May 3, 2002
Study Start
August 1, 2000
Primary Completion
October 1, 2003
Study Completion
October 1, 2003
Last Updated
January 4, 2013
Record last verified: 2013-01