NCT00024544

Brief Summary

The purpose of the study is to evaluate an investigational medication to treat chronic asthma. The research is being conducted at 20 clinical research sites in the US and is open to both men and women ages 18 to 70 years. Participants in the study will have a number of visits to a research site over an 8-month period. All study-related care and medication is provided to qualified participants at no cost. This includes all visits, examinations and laboratory work.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for phase_2 asthma

Timeline
Completed

Started Aug 2001

Typical duration for phase_2 asthma

Geographic Reach
1 country

18 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2001

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 19, 2001

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 20, 2001

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2003

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2003

Completed
Last Updated

March 7, 2012

Status Verified

March 1, 2012

Enrollment Period

1.5 years

First QC Date

September 19, 2001

Last Update Submit

March 6, 2012

Conditions

Keywords

asthmaanti-IL-4 monoclonal antibodypascolizumab

Interventions

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • At least a 6-month history of asthma
  • No use of inhaled, oral or injectable steroids for at least 1 month prior to enrollment

You may not qualify if:

  • Patients with \> 10 pack years of smoking history or smoking within 12 months of study enrollment
  • No significant disease other than asthma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (18)

Allergy Research Foundation

Los Angeles, California, 90025, United States

Location

Southern California Research

Mission Viejo, California, 92691, United States

Location

Clinical Trials of Orange Cnty., Inc.

Orange, California, 92868, United States

Location

Allergy Associates Medical Group, Inc.

San Diego, California, 92120, United States

Location

Allergy and Asthma Associates Santa Clara Valley Research Center

San Jose, California, 95117, United States

Location

Bensch Research Associates

Stockton, California, 95207, United States

Location

National Jewish Medical and Research Center

Denver, Colorado, 80206, United States

Location

ICSL Clinical Studies

Normal, Illinois, 61761, United States

Location

Respiratory Therapy and Pulmonary Clinical Research Brigham & Women's Hospital

Boston, Massachusetts, 02115, United States

Location

New England Clinical Studies

North Dartmouth, Massachusetts, 02747, United States

Location

Clinical Research Institute

Minneapolis, Minnesota, 55402, United States

Location

The Clinical Research Center, LLC

St Louis, Missouri, 63141, United States

Location

Center for Allergy, Asthma and Immunology, Creighton University

Omaha, Nebraska, 68131, United States

Location

Princeton Center for Clinical Research

Princeton, New Jersey, 08540, United States

Location

Allergy, Asthma, and Dermatology Research Center, LLC

Lake Oswego, Oregon, 97035, United States

Location

Valley Clinical Research Center

Easton, Pennsylvania, 18045, United States

Location

Clinical Trials North Houston

Houston, Texas, 77090, United States

Location

University of Wisconsin Medical School

Madison, Wisconsin, 53792, United States

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 19, 2001

First Posted

September 20, 2001

Study Start

August 1, 2001

Primary Completion

February 1, 2003

Study Completion

February 1, 2003

Last Updated

March 7, 2012

Record last verified: 2012-03

Locations