Phase II, Randomized, Open-Label Study of Switching to Protease Inhibitor-Sparing Regimens for Improvement of Metabolic Abnormalities
Sponsor study identifier
Secondary identifiers
interventional
342
1 country
11
Study Start
Not reported
Date not reportedPrimary Completion
February 2002
Actual (reported)Study Completion
Not reported
Date not reportedThe purpose of this study is to learn whether changing from a type of anti-HIV drug called a protease inhibitor (PI) to another type of anti-HIV drug will help to lower the amount of fats or sugars in the blood. PIs have been effective at keeping HIV viral load (amount of HIV in the blood) down. However, some people who take PIs have higher than normal levels of fats and/or sugars in the blood. Doctors believe that switching to anti-HIV drugs that do not contain PIs will improve the abnormal side effects. This study will test 3 different combinations of non-PI drugs to see which may improve side effects while keeping viral loads low.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
Not reported
Date not reportedClick on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 14, 2001
Actual (reported)August 31, 2001
Actual (reported)February 2002
Actual (reported)Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
These entries preserve how the registry describes the intervention. Their treatment roles are shown separately from molecular identities.
Grouped treatment entry
Abacavir sulfate, Lamivudine and Zidovudine
The registry names several treatments. This does not confirm that participants received them together or that they form a single product.
View registry recordUniv of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
Georgetown Univ Med Ctr
Washington D.C., District of Columbia, 20007, United States
Emory Univ
Atlanta, Georgia, 30308, United States
Northwestern Univ Med School
Chicago, Illinois, 60611, United States
The CORE Ctr
Chicago, Illinois, 60612, United States
Boston Med Ctr
Boston, Massachusetts, 02118, United States
Brigham and Women's Hosp
Boston, Massachusetts, 02215, United States
David Wohl
First Submitted
July 14, 2001
First Posted
August 31, 2001
Primary Completion
February 2002
Actual (reported)Last Updated
February 28, 2011
Record last verified: 2003-01
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Source: ClinicalTrials.gov.
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Beth Israel Med Ctr
New York, New York, 10003, United States
Bellevue Hosp / New York Univ Med Ctr
New York, New York, 10016, United States
Univ of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Univ of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States