Protection Against Benzene Toxicity
NQO1 in Protection Against Benzene Toxicity
1 other identifier
observational
N/A
1 country
1
Brief Summary
We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.
Trial Health
Trial Health Score
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Started Jul 1998
Typical duration for all trials
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 1998
CompletedFirst Submitted
Initial submission to the registry
February 21, 2001
CompletedFirst Posted
Study publicly available on registry
February 23, 2001
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2001
CompletedJune 24, 2005
July 1, 2002
February 21, 2001
June 23, 2005
Conditions
Keywords
Eligibility Criteria
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Sponsors & Collaborators
Study Sites (1)
University of Colorado Health Sciences Center
Denver, Colorado, 80262, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- NIH
Study Record Dates
First Submitted
February 21, 2001
First Posted
February 23, 2001
Study Start
July 1, 1998
Study Completion
June 1, 2001
Last Updated
June 24, 2005
Record last verified: 2002-07