Key Insights

Highlights

Success Rate

86% trial completion

Published Results

34 trials with published results (22%)

Research Maturity

68 completed trials (43% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

7.0%

11 terminated out of 157 trials

Success Rate

86.1%

-0.5% vs benchmark

Late-Stage Pipeline

13%

20 trials in Phase 3/4

Results Transparency

50%

34 of 68 completed with results

Key Signals

34 with results86% success11 terminated

Data Visualizations

Phase Distribution

127Total
Not Applicable (19)
Early P 1 (3)
P 1 (25)
P 2 (60)
P 3 (6)
P 4 (14)

Trial Status

Completed68
Unknown30
Recruiting19
Not Yet Recruiting15
Terminated11
Active Not Recruiting7

Trial Success Rate

86.1%

Benchmark: 86.6%

Based on 68 completed trials

Clinical Trials (157)

Showing 20 of 20 trials
NCT06398457Early Phase 1Recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

NCT07714512Phase 1RecruitingPrimary

Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia

NCT07578675RecruitingPrimary

Brain Cognitive Network Abnormalities in Anemia Patients Using fNIRS

NCT07737262Phase 3Not Yet RecruitingPrimary

Prophylactic NAC to Improve Platelet Engraftment After Haploidentical Transplantation in Severe Aplastic Anemia Patients

NCT04558736Phase 2RecruitingPrimary

Haploidentical HCT for Severe Aplastic Anemia

NCT07786922Phase 2Not Yet RecruitingPrimary

A Study of Avatrombopag in Adults With Aplastic Anemia Who Did Not Respond to, Cannot Receive, or Had Return of Disease After Standard Treatment

NCT03025698Phase 2CompletedPrimary

A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic Anemia

NCT07698080Phase 2Not Yet Recruiting

Dexamethasone, Intravenous Injection of Human Immunoglobulin, and Increased Infusion of Mononuclear Cells to Reduce Donor Specific Antibodies in Haploidentical Hematopoietic Stem Cell Transplantation

NCT01624805Phase 2RecruitingPrimary

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

NCT03622788Phase 1Active Not Recruiting

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

NCT05018936Phase 2WithdrawnPrimary

Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia

NCT06424639Phase 4WithdrawnPrimary

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

NCT06689800Not ApplicableRecruiting

Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

NCT07532408Phase 2WithdrawnPrimary

Romiplostim N01 in the Treatment of Refractory Chemoradiotherapy-induced AA

NCT06752694Phase 2Active Not RecruitingPrimary

Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia

NCT00471848Phase 2CompletedPrimary

Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic Anaemia

NCT07572084Phase 2Not Yet RecruitingPrimary

Romiplostim N01 in Chemoradiotherapy-induced Aplastic Anemia

NCT06646497Phase 2RecruitingPrimary

Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT07499102Phase 2Not Yet RecruitingPrimary

CK0801 for Treatment of Aplastic Anemia

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