The Identification of Prognostic Factors of Late Stage Disease, Particularly Those That Are Modifiable, That Might Explain the Worsened Prognosis With Colorectal Cancer Among Veterans.
CSP #707D - Colorectal Cancer-Risk Factors for Advanced Disease
1 other identifier
observational
N/A
1 country
1
Brief Summary
Colorectal cancer is the second leading cause of cancer death in the United States each year. Approximately one million veterans aged 50 and older will develop colorectal cancer over the remainder of their lives and nearly 433,000 will die from it. Because most cancers are diagnosed after local or regional spread, nearly half of all patients diagnosed with colorectal cancer will die. On a national basis, the relative five year survival with colorectal cancer was estimated at approximately 40% among veterans, substantially lower than SEER estimates in the general population of 61.7% (colon) and 59.3% (rectum). Colorectal cancer is preventable through screening, however and, if diagnosed in an early stage (Dukes' A and B), is curable. This is the first study to examine factors that might explain the worsened prognosis for veterans with colorectal cancer. If modifiable factors such as physician and patient delay in diagnosis, or poverty, explain the increased mortality among veterans, educational programs and interventions that improve the process of care associated with screening and diagnosis can be instituted.
Trial Health
Trial Health Score
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1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 1998
CompletedFirst Submitted
Initial submission to the registry
December 29, 2000
CompletedFirst Posted
Study publicly available on registry
January 1, 2001
CompletedFebruary 3, 2011
February 1, 2011
December 29, 2000
February 2, 2011
Conditions
Keywords
Study Arms (1)
1
Eligibility Criteria
You may qualify if:
- Colorectal cancer patients at the 14 participating sites
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Durham VA Medical Center HSR&D COE
Durham, North Carolina, 27705, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Dawn Provenzale, MD MS
Durham VA Medical Center HSR&D COE
Study Design
- Study Type
- observational
- Sponsor Type
- FED
Study Record Dates
First Submitted
December 29, 2000
First Posted
January 1, 2001
Study Start
January 1, 1998
Last Updated
February 3, 2011
Record last verified: 2011-02