NCT00006502

Brief Summary

To determine whether an impairment of myocardial perfusion reserve is an early indicator of coronary artery disease.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 2000

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2000

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

November 16, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 17, 2000

Completed
4.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2005

Completed
Last Updated

February 29, 2016

Status Verified

July 1, 2005

First QC Date

November 16, 2000

Last Update Submit

February 26, 2016

Conditions

Cardiovascular DiseasesCoronary ArteriosclerosisCoronary DiseaseHeart Diseases

Eligibility Criteria

AgeUp to 100 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (5)

  • Jerosch-Herold M, Swingen C, Seethamraju RT. Myocardial blood flow quantification with MRI by model-independent deconvolution. Med Phys. 2002 May;29(5):886-97. doi: 10.1118/1.1473135.

    PMID: 12033585BACKGROUND

  • Swingen C, Seethamraju RT, Jerosch-Herold M. An approach to the three-dimensional display of left ventricular function and viability using MRI. Int J Cardiovasc Imaging. 2003 Aug;19(4):325-36. doi: 10.1023/a:1025450211508.

    PMID: 14598902BACKGROUND

  • Jerosch-Herold M, Hu X, Murthy NS, Rickers C, Stillman AE. Magnetic resonance imaging of myocardial contrast enhancement with MS-325 and its relation to myocardial blood flow and the perfusion reserve. J Magn Reson Imaging. 2003 Nov;18(5):544-54. doi: 10.1002/jmri.10384.

    PMID: 14579397BACKGROUND

  • Swingen CM, Seethamraju RT, Jerosch-Herold M. Feedback-assisted three-dimensional reconstruction of the left ventricle with MRI. J Magn Reson Imaging. 2003 May;17(5):528-37. doi: 10.1002/jmri.10290.

    PMID: 12720262BACKGROUND

  • Jerosch-Herold M, Seethamraju RT, Swingen CM, Wilke NM, Stillman AE. Analysis of myocardial perfusion MRI. J Magn Reson Imaging. 2004 Jun;19(6):758-70. doi: 10.1002/jmri.20065.

    PMID: 15170782BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesCoronary Artery DiseaseCoronary DiseaseHeart Diseases

Condition Hierarchy (Ancestors)

Myocardial IschemiaArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • Michael Jerosch-Herold

    University of Minnesota

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

November 16, 2000

First Posted

November 17, 2000

Study Start

September 1, 2000

Study Completion

June 1, 2005

Last Updated

February 29, 2016

Record last verified: 2005-07